Chapter 1. A History of Allogeneic Hematopoietic Cell Transplantation

  1. Frederick R. Appelbaum MD Member Director Professor Head3,4,
  2. Stephen J. Forman MD Director Staff Physician5,6,
  3. Robert S. Negrin MD Professor of Medicine Chief7 and
  4. Karl G. Blume MD, FACP Emeritus Professor of Medicine7,8
  1. E. Donnall Thomas MD Member Professor Emeritus1,2

Published Online: 5 MAR 2009

DOI: 10.1002/9781444303537.ch1

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

How to Cite

Thomas, E. D. (2009) A History of Allogeneic Hematopoietic Cell Transplantation, in Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition (eds F. R. Appelbaum, S. J. Forman, R. S. Negrin and K. G. Blume), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303537.ch1

Editor Information

  1. 3

    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

  2. 4

    Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA

  3. 5

    Department of Hematology and Hematopoietic Cell Transplantation, Duarte, California, USA

  4. 6

    Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA

  5. 7

    Division of Blood and Marrow Transplantation, Stanford University, Stanford, California, USA

  6. 8

    Division of Bone Marrow Transplantation, Department of Medicine, Stanford University, School of Medicine, Stanford, California, USA

Author Information

  1. 1

    Fred Hutchinson Cancer Research Center, Seattle, WA, USA

  2. 2

    University of Washington School of Medicine, Nobel Laureate Medicine/Physiology, 1990, Seattle, WA, USA

Publication History

  1. Published Online: 5 MAR 2009
  2. Published Print: 27 FEB 2009

ISBN Information

Print ISBN: 9781405153485

Online ISBN: 9781444303537

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Keywords:

  • history of allogeneic hematopoietic cell transplantation;
  • hematopoietic cell transplantation (HCT);
  • marrow transplantation in therapeutic application;
  • symposium on bone marrow transplantation in Paris;
  • advances from animal studies;
  • disappointments of clinical marrow transplants in late 1950s;
  • Seattle marrow transplantation team - grant supporting clinical marrow transplantation;
  • advances in knowledge of histocompatibility;
  • Mathé ‘s “adoptive immunotherapy”

Summary

This chapter contains sections titled:

  • The beginning

  • Early clinical studies

  • Advances from animal studies

  • Advances in knowledge of histocompatibility

  • Renewed clinical studies

  • History is now

  • References