Chapter 102. Pain Management

  1. Frederick R. Appelbaum MD Member Director Professor Head5,6,
  2. Stephen J. Forman MD Director Staff Physician7,8,
  3. Robert S. Negrin MD Professor of Medicine Chief9 and
  4. Karl G. Blume MD, FACP Emeritus Professor of Medicine9,10
  1. Noelle V. Frey MD Instructor of Medicine1 and
  2. Jonathan R. Gavrin MD Director2,3,4

Published Online: 5 MAR 2009

DOI: 10.1002/9781444303537.ch102

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

How to Cite

Frey, N. V. and Gavrin, J. R. (2009) Pain Management, in Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition (eds F. R. Appelbaum, S. J. Forman, R. S. Negrin and K. G. Blume), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303537.ch102

Editor Information

  1. 5

    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

  2. 6

    Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA

  3. 7

    Department of Hematology and Hematopoietic Cell Transplantation, Duarte, California, USA

  4. 8

    Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA

  5. 9

    Division of Blood and Marrow Transplantation, Stanford University, Stanford, California, USA

  6. 10

    Division of Bone Marrow Transplantation, Department of Medicine, Stanford University, School of Medicine, Stanford, California, USA

Author Information

  1. 1

    Division of Hematology-Oncology, Abramson Cancer Center University of Pennsylvania, Philadelphia, Pennsylvania, USA

  2. 2

    Symptom Management and Palliative Care Interim Director, USA

  3. 3

    Pain Management Services, Physician Co-chair HUP Ethics Committee Department of Anesthesiology and Critical Care, USA

  4. 4

    Department of Medicine Hospital of the University of Pennsylvania, USA

Publication History

  1. Published Online: 5 MAR 2009
  2. Published Print: 27 FEB 2009

ISBN Information

Print ISBN: 9781405153485

Online ISBN: 9781444303537



  • pain management;
  • common sources of pain in bone marrow transplantation;
  • pain - multidimensional experience;
  • pain measurement and monitoring;
  • assessment of pain and treatment efficacy;
  • ability to function;
  • medication use and side-effects;
  • pain diagnostics and therapy selection;
  • nonpharmacologic techniques in pain management;
  • cognitive-behavioral strategies


This chapter contains sections titled:

  • Introduction

  • Anatomy and physiology of pain

  • The clinical phenomenon of pain

  • Assessment of pain and treatment efficacy

  • Nonpharmacologic techniques in pain management

  • Nonopioid pharmacologic management of pain

  • Opioids in the management of pain

  • Clinical pain management in the HCT patient

  • Analgesia/sedation for painful and unpleasant procedures

  • Invasive analgesic techniques in the HCT patient

  • Analgesia and sedation in dying patients

  • Conclusion

  • References