Chapter 107. Neurologic Complications of Hematopoietic Cell Transplantation

  1. Frederick R. Appelbaum MD Member Director Professor Head2,3,
  2. Stephen J. Forman MD Director Staff Physician4,5,
  3. Robert S. Negrin MD Professor of Medicine Chief6 and
  4. Karl G. Blume MD, FACP Emeritus Professor of Medicine6,7
  1. Harry Openshaw MD

Published Online: 5 MAR 2009

DOI: 10.1002/9781444303537.ch107

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

How to Cite

Openshaw, H. (2009) Neurologic Complications of Hematopoietic Cell Transplantation, in Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition (eds F. R. Appelbaum, S. J. Forman, R. S. Negrin and K. G. Blume), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303537.ch107

Editor Information

  1. 2

    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

  2. 3

    Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA

  3. 4

    Department of Hematology and Hematopoietic Cell Transplantation, Duarte, California, USA

  4. 5

    Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA

  5. 6

    Division of Blood and Marrow Transplantation, Stanford University, Stanford, California, USA

  6. 7

    Division of Bone Marrow Transplantation, Department of Medicine, Stanford University, School of Medicine, Stanford, California, USA

Author Information

  1. City of Hope National Medical Center, Duarte, California, USA

Publication History

  1. Published Online: 5 MAR 2009
  2. Published Print: 27 FEB 2009

ISBN Information

Print ISBN: 9781405153485

Online ISBN: 9781444303537

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Keywords:

  • neurologic complications of hematopoietic cell transplantation;
  • immune-mediated complications;
  • complications from calcineurin inhibitors;
  • complications from immunosuppressive drugs;
  • pretransplant neurologic screening;
  • complications from supportive care and other drugs

Summary

This chapter contains sections titled:

  • Introduction

  • Common neurologic symptoms and signs in transplant patients

  • Infectious complications

  • Cerebrovascular complications

  • Metabolic complications

  • Immune-mediated complications

  • Complications from calcineurin inhibitors, CSP, and tacrolimus

  • Complications from other immunosuppressive drugs

  • Complications from conditioning agents

  • Complications from supportive care and other drugs

  • Pretransplant neurologic screening

  • Conclusion

  • References