Chapter 53. Hematopoietic Cell Transplantation for Adult Acute Myeloid Leukemia

  1. Frederick R. Appelbaum MD Member Director Professor Head1,2,
  2. Stephen J. Forman MD Director Staff Physician3,4,
  3. Robert S. Negrin MD Professor of Medicine Chief5 and
  4. Karl G. Blume MD, FACP Emeritus Professor of Medicine5,6
  1. Frederick R. Appelbaum MD Member Director Professor Head1,2

Published Online: 5 MAR 2009

DOI: 10.1002/9781444303537.ch53

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

How to Cite

Appelbaum, F. R. (2009) Hematopoietic Cell Transplantation for Adult Acute Myeloid Leukemia, in Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition (eds F. R. Appelbaum, S. J. Forman, R. S. Negrin and K. G. Blume), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303537.ch53

Editor Information

  1. 1

    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

  2. 2

    Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA

  3. 3

    Department of Hematology and Hematopoietic Cell Transplantation, Duarte, California, USA

  4. 4

    Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA

  5. 5

    Division of Blood and Marrow Transplantation, Stanford University, Stanford, California, USA

  6. 6

    Division of Bone Marrow Transplantation, Department of Medicine, Stanford University, School of Medicine, Stanford, California, USA

Author Information

  1. 1

    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

  2. 2

    Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA

Publication History

  1. Published Online: 5 MAR 2009
  2. Published Print: 27 FEB 2009

ISBN Information

Print ISBN: 9781405153485

Online ISBN: 9781444303537

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Keywords:

  • hematopoietic cell transplantation for adult acute myeloid leukemia;
  • postremission chemotherapy;
  • mutations not detectable on routine cytogenetics;
  • RAS mutations;
  • nucleophosmin mutations;
  • retinoic acid receptor-alpha translocations;
  • chemotherapy for recurrent AML;
  • nontransplant approach to treatment;
  • untreated first relapse

Summary

This chapter contains sections titled:

  • Introduction

  • Epidemiology and etiology

  • Molecular and cellular

  • Classification

  • Clinical and laboratory presentation

  • Nontransplant approach to treatment

  • Hematopoietic cell transplantation

  • Conclusion

  • References