Chapter 58. Hematopoietic Cell Transplantation for Multiple Myeloma

  1. Frederick R. Appelbaum MD Member Director Professor Head3,4,
  2. Stephen J. Forman MD Director Staff Physician5,6,
  3. Robert S. Negrin MD Professor of Medicine Chief7 and
  4. Karl G. Blume MD, FACP Emeritus Professor of Medicine7,8
  1. Muzaffar H. Qazilbash MD Associate Professor of Medicine1 and
  2. Sergio A. Giralt MD Professor of Medicine2

Published Online: 5 MAR 2009

DOI: 10.1002/9781444303537.ch58

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

How to Cite

Qazilbash, M. H. and Giralt, S. A. (2009) Hematopoietic Cell Transplantation for Multiple Myeloma, in Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition (eds F. R. Appelbaum, S. J. Forman, R. S. Negrin and K. G. Blume), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303537.ch58

Editor Information

  1. 3

    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

  2. 4

    Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA

  3. 5

    Department of Hematology and Hematopoietic Cell Transplantation, Duarte, California, USA

  4. 6

    Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA

  5. 7

    Division of Blood and Marrow Transplantation, Stanford University, Stanford, California, USA

  6. 8

    Division of Bone Marrow Transplantation, Department of Medicine, Stanford University, School of Medicine, Stanford, California, USA

Author Information

  1. 1

    Department of Stem Cell Transplantation and Cellular Therapy, M.D. Anderson Cancer Center, Houston, Texas, USA

  2. 2

    Department of Stem Cell Transplantation and Cellular Therapy, University of Texas, MD Anderson Cancer Center, Houston, Texas, USA

Publication History

  1. Published Online: 5 MAR 2009
  2. Published Print: 27 FEB 2009

ISBN Information

Print ISBN: 9781405153485

Online ISBN: 9781444303537

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Keywords:

  • hematopoietic cell transplantation for multiple myeloma;
  • Staging, prognosis and response;
  • Nontransplantation approaches;
  • patients not eligible for autologous HCT;
  • purging of myeloma cells;
  • timing of autologous HCT;
  • single versus tandem autologous transplantation;
  • allogeneic HCT in myeloma;
  • allogeneic HCT with reduced-intensity conditioning

Summary

This chapter contains sections titled:

  • Epidemiology and etiology

  • Molecular and cellular biology

  • Clinical description

  • Nontransplantation approaches

  • Autologous HCT

  • Allogeneic HCT in myeloma

  • Current status and future directions of HCT in myeloma: moving beyond high-dose melphalan

  • The emerging role of maintenance therapy

  • Summary

  • Acknowledgement

  • References