Chapter 68. Hematopoietic Cell Transplantation for Patients with Human Immunodeficiency Virus Infection

  1. Frederick R. Appelbaum MD Member Director Professor Head2,3,
  2. Stephen J. Forman MD Director Staff Physician4,5,
  3. Robert S. Negrin MD Professor of Medicine Chief6 and
  4. Karl G. Blume MD, FACP Emeritus Professor of Medicine6,7
  1. John A. Zaia MD Chair,
  2. Amrita Krishnan and
  3. John J. Rossi

Published Online: 5 MAR 2009

DOI: 10.1002/9781444303537.ch68

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

How to Cite

Zaia, J. A., Krishnan, A. and Rossi, J. J. (2009) Hematopoietic Cell Transplantation for Patients with Human Immunodeficiency Virus Infection, in Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition (eds F. R. Appelbaum, S. J. Forman, R. S. Negrin and K. G. Blume), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303537.ch68

Editor Information

  1. 2

    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

  2. 3

    Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA

  3. 4

    Department of Hematology and Hematopoietic Cell Transplantation, Duarte, California, USA

  4. 5

    Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA

  5. 6

    Division of Blood and Marrow Transplantation, Stanford University, Stanford, California, USA

  6. 7

    Division of Bone Marrow Transplantation, Department of Medicine, Stanford University, School of Medicine, Stanford, California, USA

Author Information

  1. Division of Virology, Beckman Research Institute of City of Hope, Duarte, California, USA

Publication History

  1. Published Online: 5 MAR 2009
  2. Published Print: 27 FEB 2009

ISBN Information

Print ISBN: 9781405153485

Online ISBN: 9781444303537

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Keywords:

  • hematopoietic cell transplantation for patients with human immunodeficiency virus infection;
  • replication and T-lymphocyte homeostasis;
  • cellular and anatomic reservoirs of HIV;
  • HCT for AIDS lymphoma;
  • strategies for cell-based gene therapy of AIDS;
  • T lymphocytes as targets for gene therapy

Summary

This chapter contains sections titled:

  • Introduction

  • Molecular and clinical biology

  • Clinical description

  • Nontransplant approaches to AIDS-related lymphoma treatment

  • HCT for AIDS lymphoma

  • Allogeneic HCT and AIDS

  • Strategies for cell-based gene therapy of AIDS

  • Molecular targets for HIV-1 gene therapy

  • RNA-based suppressors

  • Protein-based suppressors

  • Current application of cell-based gene therapy to AIDS

  • T lymphocytes as targets for gene therapy

  • HSCs as targets of gene transfer

  • Conclusion

  • References