Chapter 82. Principles of Transfusion Support Before and After Hematopoietic Cell Transplantation

  1. Frederick R. Appelbaum MD Member Director Professor Head2,3,
  2. Stephen J. Forman MD Director Staff Physician4,5,
  3. Robert S. Negrin MD Professor of Medicine Chief6 and
  4. Karl G. Blume MD, FACP Emeritus Professor of Medicine6,7
  1. Jeffrey McCullough MD

Published Online: 5 MAR 2009

DOI: 10.1002/9781444303537.ch82

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

How to Cite

McCullough, J. (2009) Principles of Transfusion Support Before and After Hematopoietic Cell Transplantation, in Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition (eds F. R. Appelbaum, S. J. Forman, R. S. Negrin and K. G. Blume), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303537.ch82

Editor Information

  1. 2

    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

  2. 3

    Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA

  3. 4

    Department of Hematology and Hematopoietic Cell Transplantation, Duarte, California, USA

  4. 5

    Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA

  5. 6

    Division of Blood and Marrow Transplantation, Stanford University, Stanford, California, USA

  6. 7

    Division of Bone Marrow Transplantation, Department of Medicine, Stanford University, School of Medicine, Stanford, California, USA

Author Information

  1. Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA

Publication History

  1. Published Online: 5 MAR 2009
  2. Published Print: 27 FEB 2009

ISBN Information

Print ISBN: 9781405153485

Online ISBN: 9781444303537

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Keywords:

  • principles of transfusion before and after hematopoietic cell transplantation;
  • hemapatopoietic cell transplantation (HCT);
  • red blood cells (RBCs);
  • leukocyte-reduced red cells;
  • transfusion of platelets;
  • prevention of alloimmunization and platelet refractoriness;
  • prevention of transfusion-transmitted CMV infection;
  • nonimmunologic complications of blood transfusion

Summary

This chapter contains sections titled:

  • Introduction

  • Red blood cell components

  • Coagulation factor components

  • Platelet components

  • Transfusion of platelets

  • Granulocyte concentrates and granulocyte transfusion

  • Transfusion strategies in HCT

  • Prevention of transfusion-transmitted CMV infection

  • Prevention of transfusion-associated GVHD

  • Transfusion therapy for HCT donors

  • Conclusion

  • Acknowledgment

  • References