Chapter 93. Epstein–Barr Virus Infection

  1. Frederick R. Appelbaum MD Member Director Professor Head3,4,
  2. Stephen J. Forman MD Director Staff Physician5,6,
  3. Robert S. Negrin MD Professor of Medicine Chief7 and
  4. Karl G. Blume MD, FACP Emeritus Professor of Medicine7,8
  1. Wen-Son Hsieh MD Assistant Professor1 and
  2. Richard F. Ambinder MD, PhD Professor2

Published Online: 5 MAR 2009

DOI: 10.1002/9781444303537.ch93

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition

How to Cite

Hsieh, W.-S. and Ambinder, R. F. (2009) Epstein–Barr Virus Infection, in Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition (eds F. R. Appelbaum, S. J. Forman, R. S. Negrin and K. G. Blume), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303537.ch93

Editor Information

  1. 3

    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

  2. 4

    Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington, USA

  3. 5

    Department of Hematology and Hematopoietic Cell Transplantation, Duarte, California, USA

  4. 6

    Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA

  5. 7

    Division of Blood and Marrow Transplantation, Stanford University, Stanford, California, USA

  6. 8

    Division of Bone Marrow Transplantation, Department of Medicine, Stanford University, School of Medicine, Stanford, California, USA

Author Information

  1. 1

    Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA

  2. 2

    Departments of Oncology, Pathology, Pharmacology and Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA

Publication History

  1. Published Online: 5 MAR 2009
  2. Published Print: 27 FEB 2009

ISBN Information

Print ISBN: 9781405153485

Online ISBN: 9781444303537

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Keywords:

  • Epstein–Barr virus-associated lymphoproliferative disorder (EBV-LPD);
  • EBV biology and pathogenesis;
  • EBV DNA in plasma;
  • PBMC versus plasma versus whole blood;
  • virologic aspects;
  • viral copy number measurements and guidelines for interpretation

Summary

This chapter contains sections titled:

  • Introduction

  • Aspects of EBV biology and pathogenesis

  • EBV-LPD in HCT

  • Clinical and pathologic aspects

  • Virologic aspects

  • Viral copy number and monitoring

  • Treatment

  • T-cell therapy for EBV-associated tumors

  • Summary

  • References