Chapter 19. Monitoring New Anticoagulants

  1. Steve Kitchen PhD Clinical Scientist Scientific Director2,3,4,
  2. John D. Olson MD, PhD Professor Vice Chair for Clinical Affairs5 and
  3. F. Eric Preston MD, FRCPath, FRCP Emeritus Professor of Hematology Director6,7
  1. E. Gray PhD and
  2. T. W. Barrowcliffe PhD

Published Online: 4 MAR 2009

DOI: 10.1002/9781444303575.ch19

Quality in Laboratory Hemostasis and Thrombosis

Quality in Laboratory Hemostasis and Thrombosis

How to Cite

Gray, E. and Barrowcliffe, T. W. (2008) Monitoring New Anticoagulants, in Quality in Laboratory Hemostasis and Thrombosis (eds S. Kitchen, J. D. Olson and F. E. Preston), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303575.ch19

Editor Information

  1. 2

    Sheffield Hemophilia and Thrombosis Centre, Royal Hallamshire Hospital, Sheffield, UK

  2. 3

    UK National External Quality Assessment Scheme (EQAS) for Blood Coagulation, Sheffield, UK

  3. 4

    WHO and WFH International External Quality Assessment Programs for Blood Coagulation, Sheffield, UK

  4. 5

    Department of Pathology, University of Texas Health Science Center, San Antonio, Texas, USA

  5. 6

    University of Sheffield, Sheffield, UK

  6. 7

    WHO and WFH International External Quality Assessment Programs for Blood Coagulation, Rutledge Mews, Sheffield, UK

Author Information

  1. National Institute for Biological Standards and Control, Potters Bar, UK

Publication History

  1. Published Online: 4 MAR 2009
  2. Published Print: 19 DEC 2008

ISBN Information

Print ISBN: 9781405168038

Online ISBN: 9781444303575

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Keywords:

  • monitoring new anticoagulants;
  • methods for monitoring indirect FXa inhibitors;
  • calibration for accuracy of measurement;
  • methods for monitoring dual inhibitor of FXa and thrombin;
  • monitoring anticoagulants using global tests;
  • new anticoagulants - classified into FXa and thrombin inhibitors

Summary

This chapter contains sections titled:

  • New anticoagulants

  • Calibration for accuracy of measurement

  • Methods for monitoring indirect FXa inhibitors

  • Methods for monitoring direct FXa inhibitors

  • Methods for monitoring dual inhibitor of FXa and thrombin

  • Methods for monitoring direct thrombin inhibitors

  • Monitoring anticoagulants using global tests

  • Conclusions

  • References