Chapter 7. Initial Evaluation of Hemostasis: Reagent and Method Selection

  1. Steve Kitchen PhD Clinical Scientist Scientific Director2,3,4,
  2. John D. Olson MD, PhD Professor Vice Chair for Clinical Affairs5 and
  3. F. Eric Preston MD, FRCPath, FRCP Emeritus Professor of Hematology Director6,7
  1. W. L. Chandler MD

Published Online: 4 MAR 2009

DOI: 10.1002/9781444303575.ch7

Quality in Laboratory Hemostasis and Thrombosis

Quality in Laboratory Hemostasis and Thrombosis

How to Cite

Chandler, W. L. (2008) Initial Evaluation of Hemostasis: Reagent and Method Selection, in Quality in Laboratory Hemostasis and Thrombosis (eds S. Kitchen, J. D. Olson and F. E. Preston), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303575.ch7

Editor Information

  1. 2

    Sheffield Hemophilia and Thrombosis Centre, Royal Hallamshire Hospital, Sheffield, UK

  2. 3

    UK National External Quality Assessment Scheme (EQAS) for Blood Coagulation, Sheffield, UK

  3. 4

    WHO and WFH International External Quality Assessment Programs for Blood Coagulation, Sheffield, UK

  4. 5

    Department of Pathology, University of Texas Health Science Center, San Antonio, Texas, USA

  5. 6

    University of Sheffield, Sheffield, UK

  6. 7

    WHO and WFH International External Quality Assessment Programs for Blood Coagulation, Rutledge Mews, Sheffield, UK

Author Information

  1. Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA

Publication History

  1. Published Online: 4 MAR 2009
  2. Published Print: 19 DEC 2008

ISBN Information

Print ISBN: 9781405168038

Online ISBN: 9781444303575

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Keywords:

  • initial evaluation of hemostasis;
  • selecting test methodology and determining clinical questions;
  • methodology and specific instrument– reagent combination evaluation;
  • prothrombin time method selection;
  • oral anticoagulant (OAC) therapy;
  • factors potentially affecting prothrombin time (PT) assay;
  • activated partial thromboplastin time method selection;
  • fibrinogen method selection;
  • thrombin time use in hemostasis evaluation and anticoagulant and antibody detection

Summary

This chapter contains sections titled:

  • Instrument selection

  • Evaluation of the method

  • Prothrombin time method selection

  • Activated partial thromboplastin time method selection

  • Fibrinogen method selection

  • Thrombin time method selection

  • References