Chapter 8. Point-of-Care Testing in Hemostasis

  1. Steve Kitchen PhD Clinical Scientist Scientific Director3,4,5,
  2. John D. Olson MD, PhD Professor Vice Chair for Clinical Affairs6 and
  3. F. Eric Preston MD, FRCPath, FRCP Emeritus Professor of Hematology Director7,8
  1. C. Gardiner PhD1,
  2. S. Machin FRCP, FRCPath1,2 and
  3. I. Mackie PhD1,2

Published Online: 4 MAR 2009

DOI: 10.1002/9781444303575.ch8

Quality in Laboratory Hemostasis and Thrombosis

Quality in Laboratory Hemostasis and Thrombosis

How to Cite

Gardiner, C., Machin, S. and Mackie, I. (2008) Point-of-Care Testing in Hemostasis, in Quality in Laboratory Hemostasis and Thrombosis (eds S. Kitchen, J. D. Olson and F. E. Preston), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303575.ch8

Editor Information

  1. 3

    Sheffield Hemophilia and Thrombosis Centre, Royal Hallamshire Hospital, Sheffield, UK

  2. 4

    UK National External Quality Assessment Scheme (EQAS) for Blood Coagulation, Sheffield, UK

  3. 5

    WHO and WFH International External Quality Assessment Programs for Blood Coagulation, Sheffield, UK

  4. 6

    Department of Pathology, University of Texas Health Science Center, San Antonio, Texas, USA

  5. 7

    University of Sheffield, Sheffield, UK

  6. 8

    WHO and WFH International External Quality Assessment Programs for Blood Coagulation, Rutledge Mews, Sheffield, UK

Author Information

  1. 1

    Hematology Department, University College London Hospitals NHS Trust, London, UK

  2. 2

    Hemostasis Research Unit, Hematology Department, University College London, London, UK

Publication History

  1. Published Online: 4 MAR 2009
  2. Published Print: 19 DEC 2008

ISBN Information

Print ISBN: 9781405168038

Online ISBN: 9781444303575

SEARCH

Keywords:

  • point-of-care testing (POCT) and near-patient testing (NPT);
  • oral anticoagulant therapy (OAT);
  • oral anticoagulation monitoring;
  • suitable quality control (QC) system to ensure validity of results;
  • quality assurance of point-of-care INR monitors;
  • patient self-monitoring of oral anticoagulation;
  • activated partial thromboplastin time testing;
  • POCT device for monitoring low molecular weight heparin (LMWH);
  • thrombelastograph TEG/ROTEM in cardiac surgery and liver transplant procedures

Summary

This chapter contains sections titled:

  • Monitoring of oral anticoagulation

  • Quality assurance of point-of-care INR monitors

  • Patient self-monitoring of oral anticoagulation

  • Activated partial thromboplastin time testing

  • Activated clotting time

  • Thrombin time

  • Low molecular weight heparin monitoring

  • D-dimer

  • Thrombelastography

  • Management of POCT services

  • Conclusions

  • References