Chapter 3. Partial or Selective Fluorination

  1. Richard D. Chambers FRS Emeritus Professor of Chemistry

Published Online: 3 MAR 2009

DOI: 10.1002/9781444305371.ch3

Fluorine in Organic Chemistry

Fluorine in Organic Chemistry

How to Cite

Chambers, R. D. (2004) Partial or Selective Fluorination, in Fluorine in Organic Chemistry, Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444305371.ch3

Author Information

  1. University of Durham, UK

Publication History

  1. Published Online: 3 MAR 2009
  2. Published Print: 8 SEP 2004

ISBN Information

Print ISBN: 9781405107877

Online ISBN: 9781444305371



  • partial or selective fluorination;
  • displacement of halogen by fluoride ion;
  • alkali metal fluorides;
  • other sources of fluoride ion;
  • replacement of hydrogen by fluorine;
  • fluorination of oxygen-containing functional groups;
  • replacement of hydroxyl groups by fluorine;
  • fluorination of nitrogen-containing functional groups;
  • addition to alkenes and alkynes


This chapter contains sections titled:

  • Introduction

  • Displacement of Halogen by Fluoride Ion

  • Replacement of Hydrogen by Fluorine

  • Fluorination of Oxygen-Containing Functional Groups

  • Fluorination of Sulphur-Containing Functional Groups

  • Fluorination of Nitrogen-Containing Functional Groups

  • Addition to Alkenes and Alkynes

  • References