Chapter 4. Utility of Chemical Derivatization Schemes for Peptide Mass Fingerprinting

  1. J. M. Rosenfeld
  1. Jonathan A. Karty,
  2. Tae-Young Kim,
  3. James P. Reilly

Published Online: 3 MAR 2009

DOI: 10.1002/9781444305500.ch4

Book Title

Sample Preparation for Hyphenated Analytical Techniques

Sample Preparation for Hyphenated Analytical Techniques

Additional Information

How to Cite

Karty, J. A., Kim, T.-Y. and Reilly, J. P. (2009) Utility of Chemical Derivatization Schemes for Peptide Mass Fingerprinting, in Sample Preparation for Hyphenated Analytical Techniques (ed J. M. Rosenfeld), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444305500.ch4

Editor Information

  1. Faculty of Health Science, McMaster University, 1200 Main Street W, Hamilton, Ontario, Canada L8N 3Z5

Author Information

  1. Department of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN 47405-7102, USA

Publication History

  1. Published Online: 3 MAR 2009
  2. Published Print: 27 SEP 2004

ISBN Information

Print ISBN: 9781405111065

Online ISBN: 9781444305500

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CHAPTER TOOLS

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Keywords:

  • utility of chemical derivatization schemes for peptide mass fingerprinting;
  • chemical derivatization for peptide mass fingerprinting;
  • matrix assisted laser desorption/ionization (MALDI);
  • infrared multi-photon dissociation (IRMPD);
  • sample preparation for hyphenated analyses;
  • MALDI-TOF peptide mass mapping;
  • 1D polyacrylamide gel electrophoresis (PAGE) to separate proteins;
  • guanidination increasing peptide mass mapping efficacy

Summary

This chapter contains sections titled:

  • Introduction

  • Experimental methodology

  • Results

  • Discussion

  • Conclusions

  • Acknowledgements

  • References

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