Chapter 9. Studies on Animal to Instrument Hyphenation: Development of Separation-Based Sensors for near Real-Time Monitoring of Drugs and Neurotransmitters
- J. M. Rosenfeld
Published Online: 3 MAR 2009
DOI: 10.1002/9781444305500.ch9
Copyright © 2004 Blackwell Publishing Ltd
Book Title
Sample Preparation for Hyphenated Analytical Techniques
Additional Information
How to Cite
Davies, M., Huynh, B., Logan, S., Heppert, K. and Lunte, S. (2009) Studies on Animal to Instrument Hyphenation: Development of Separation-Based Sensors for near Real-Time Monitoring of Drugs and Neurotransmitters, in Sample Preparation for Hyphenated Analytical Techniques (ed J. M. Rosenfeld), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444305500.ch9
Editor Information
Faculty of Health Science, McMaster University, 1200 Main Street W, Hamilton, Ontario, Canada L8N 3Z5
Publication History
- Published Online: 3 MAR 2009
- Published Print: 27 SEP 2004
ISBN Information
Print ISBN: 9781405111065
Online ISBN: 9781444305500
- Summary
- Chapter
Keywords:
- classical methods for sampling and analyzing blood and tissue;
- animal to instrument hyphenation;
- sample preparation for hyphenated analyses;
- intact animal studies - anesthetized vs recovered;
- classical methods of tissue sampling;
- ultrafiltration (UF);
- microdialysis sampling in live animal system;
- analytical system detector output;
- UF and automated blood sampling and removing fluids from animal;
- coupling online sampling technique directly with separation methods
Summary
This chapter contains sections titled:
Introduction
Obtaining in vivo biological samples by classical techniques: limitations, challenges and other considerations
Modern in vivo sampling techniques
Analytical methodologies for online microdialysis sampling
Conclusions
Acknowledgements
References