Chapter 5. Speed and Efficiency in the Production of Diverse Structures: Microwave-Assisted Multi-Component Reactions

  1. Jason P. Tierney2 and
  2. Pelle Lidström3
  1. Jacob Westman Associate Professor

Published Online: 3 MAR 2009

DOI: 10.1002/9781444305548.ch5

Microwave Assisted Organic Synthesis

Microwave Assisted Organic Synthesis

How to Cite

Westman, J. (2005) Speed and Efficiency in the Production of Diverse Structures: Microwave-Assisted Multi-Component Reactions, in Microwave Assisted Organic Synthesis (eds J. P. Tierney and P. Lidström), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444305548.ch5

Editor Information

  1. 2

    GlaxoSmithKline, Harlow, UK

  2. 3

    Biotage AB, Uppsala, Sweden

Author Information

  1. MedChemCon, Ålands-Västerby, SE-74020 Vänge, Sweden

Publication History

  1. Published Online: 3 MAR 2009
  2. Published Print: 24 MAY 2005

ISBN Information

Print ISBN: 9781405175906

Online ISBN: 9781444305548

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Keywords:

  • speed and efficiency in production of diverse structures;
  • multi-component reactions;
  • famous Ugi reaction - ‘one-pot’ condensation of carboxylic acid, amine, aldehyde or ketone;
  • amino-functionalised TentaGel resin (TentaGel S RAM);
  • Gewald synthesis of 2-acyl amino thiophenes;
  • aza-Diels–Alder reaction of Danishefsky's diene with imines;
  • multi-component reactions using isatoic anhydride

Summary

This chapter contains sections titled:

  • Background

  • Multi-component reactions

  • Versatile reagents in multi-component reactions

  • Miscellaneous products

  • Summary

  • References