Chapter 14. Dysglycemia and the Risk of Cardiovascular Events

  1. Salim Yusuf DPhil, FRCPC, FRSC Research Chair Professor of Medicine Director Vice President Research3,4,5,
  2. John A Cairns MD, FRCPC Professor of Medicine Former Dean6,
  3. A John Camm MD British Heart Foundation Professor Head of Cardiac7,
  4. Ernest L Fallen MD, FRCPC Professor Emeritus8 and
  5. Bernard J Gersh MB, ChB, DPhil Consultant Professor of Medicine9
  1. Hertzel C Gerstein MD, MSc, FRCPC1 and
  2. Zubin Punthakee MD2

Published Online: 21 MAY 2010

DOI: 10.1002/9781444309768.ch14

Evidence-Based Cardiology, Third Edition

Evidence-Based Cardiology, Third Edition

How to Cite

Gerstein, H. C. and Punthakee, Z. (2009) Dysglycemia and the Risk of Cardiovascular Events, in Evidence-Based Cardiology, Third Edition (eds S. Yusuf, J. A. Cairns, A. J. Camm, E. L. Fallen and B. J. Gersh), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444309768.ch14

Editor Information

  1. 3

    McMaster University, Canada

  2. 4

    Population Health Research Institute, McMaster University, Hamilton Health Sciences, Canada

  3. 5

    Hamilton Health Sciences, Hamilton, Ontario, Canada

  4. 6

    Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada

  5. 7

    St George's University of London, London, UK

  6. 8

    McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

  7. 9

    Mayo Clinic College of Medicine, Rochester, MN, USA

Author Information

  1. 1

    Division of Endocrinology and Metabolism, Population Health Research Institute, Department of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada

  2. 2

    Department of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada

Publication History

  1. Published Online: 21 MAY 2010
  2. Published Print: 13 NOV 2009

ISBN Information

Print ISBN: 9781405159258

Online ISBN: 9781444309768

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Keywords:

  • dysglycemia - risk of cardiovascular events;
  • diabetes mellitus - common chronic condition defined on the basis of high glucose levels;
  • glycation of variety of proteins - promoting CVD;
  • glucose metabolism - promoting cellular damage;
  • patients with CVD - increased levels of proinsulin and split products;
  • hyperglycemia and CVD;
  • dysglycemia - independent risk factor for CVD

Summary

This chapter contains sections titled:

  • Introduction

  • What is diabetes and how common is it?

  • How much does dysglycemia increase cardiovascular risk?

  • Explanation of the dysglycemia-cardiovascular disease connection

  • Does glucose lowering reduce cardiovascular outcomes?

  • Conclusion

  • References