Chapter 17. The Social Determinants of Cardiovascular Disease

  1. Salim Yusuf DPhil, FRCPC, FRSC Research Chair Professor of Medicine Director Vice President Research3,4,5,
  2. John A Cairns MD, FRCPC Professor of Medicine Former Dean6,
  3. A John Camm MD British Heart Foundation Professor Head of Cardiac7,
  4. Ernest L Fallen MD, FRCPC Professor Emeritus8 and
  5. Bernard J Gersh MB, ChB, DPhil Consultant Professor of Medicine9
  1. Martin McKee MD, DSc, FRCP, FRCPI, FFPH, FMedSci, CBE Professor1 and
  2. Clara K Chow MBBS, FRACP, PhD Senior Research Fellow2

Published Online: 21 MAY 2010

DOI: 10.1002/9781444309768.ch17

Evidence-Based Cardiology, Third Edition

Evidence-Based Cardiology, Third Edition

How to Cite

McKee, M. and Chow, C. K. (2009) The Social Determinants of Cardiovascular Disease, in Evidence-Based Cardiology, Third Edition (eds S. Yusuf, J. A. Cairns, A. J. Camm, E. L. Fallen and B. J. Gersh), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444309768.ch17

Editor Information

  1. 3

    McMaster University, Canada

  2. 4

    Population Health Research Institute, McMaster University, Hamilton Health Sciences, Canada

  3. 5

    Hamilton Health Sciences, Hamilton, Ontario, Canada

  4. 6

    Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada

  5. 7

    St George's University of London, London, UK

  6. 8

    McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

  7. 9

    Mayo Clinic College of Medicine, Rochester, MN, USA

Author Information

  1. 1

    European Centre on Health of Societies in Transition, London School of Hygiene and Tropical Medicine, London, UK

  2. 2

    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada

Publication History

  1. Published Online: 21 MAY 2010
  2. Published Print: 13 NOV 2009

ISBN Information

Print ISBN: 9781405159258

Online ISBN: 9781444309768



  • social determinants - cardiovascular disease;
  • risk factors - abnormal lipids, smoking, hypertension, diabetes;
  • risk of CVD - influenced by environment that individual inhabits;
  • dominant explanatory models - demand-control model, effort-reward imbalance model;
  • mechanisms and interpretation - hypothalamic-pituitary-adrenal axis, inflammation, coagulation;
  • psychosocial factors - epidemiology of cardiovascular disease;
  • risk factors for cardiovascular disease - smoking, physical inactivity, poor nutrition


This chapter contains sections titled:

  • Introduction

  • Family networks

  • Social networks

  • The work environment

  • Mechanisms and interpretation

  • The broader environment

  • Conclusion

  • References