Chapter 31. Reperfusion Therapies for St Segment Elevation Myocardial Infarction

  1. Salim Yusuf DPhil, FRCPC, FRSC Research Chair Professor of Medicine Director Vice President Research5,6,7,
  2. John A Cairns MD, FRCPC Professor of Medicine Former Dean8,
  3. A John Camm MD British Heart Foundation Professor Head of Cardiac9,
  4. Ernest L Fallen MD, FRCPC Professor Emeritus10 and
  5. Bernard J Gersh MB, ChB, DPhil Consultant Professor of Medicine11
  1. Joseph B Muhlestein MD, FACC Professor of Medicine Director1,2 and
  2. Jeffrey L Anderson MD, FACC, FAHA, MACP Professor Associate Chief of Cardiology Vice Chair for Research3,4

Published Online: 21 MAY 2010

DOI: 10.1002/9781444309768.ch31

Evidence-Based Cardiology, Third Edition

Evidence-Based Cardiology, Third Edition

How to Cite

Muhlestein, J. B. and Anderson, J. L. (2009) Reperfusion Therapies for St Segment Elevation Myocardial Infarction, in Evidence-Based Cardiology, Third Edition (eds S. Yusuf, J. A. Cairns, A. J. Camm, E. L. Fallen and B. J. Gersh), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444309768.ch31

Editor Information

  1. 5

    McMaster University, Canada

  2. 6

    Population Health Research Institute, McMaster University, Hamilton Health Sciences, Canada

  3. 7

    Hamilton Health Sciences, Hamilton, Ontario, Canada

  4. 8

    Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada

  5. 9

    St George's University of London, London, UK

  6. 10

    McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

  7. 11

    Mayo Clinic College of Medicine, Rochester, MN, USA

Author Information

  1. 1

    University of Utah, UT, USA

  2. 2

    Cardiovascular Department, Cardiology Research, Intermountain Medical Center, Murray, UT, USA

  3. 3

    Internal Medicine, University of Utah School of Medicine, UT, USA

  4. 4

    Intermountain Medical Center, Salt Lake City, UT, USA

Publication History

  1. Published Online: 21 MAY 2010
  2. Published Print: 13 NOV 2009

ISBN Information

Print ISBN: 9781405159258

Online ISBN: 9781444309768



  • reperfusion therapies for ST segment elevation myocardial infarction;
  • historic perspective - fibrinolytic therapy first developed and validated;
  • fibrinolytic agents - general mechanisms of action and pharmacologic properties;
  • primary angioplasty - primary percutaneous coronary intervention (PCI);
  • efficacy of intravenous fibrinolytic therapy - effects of coronary arterial patency


This chapter contains sections titled:

  • Introduction

  • Historic perspective

  • Fibrinolytic agents

  • Primary angioplasty

  • Conclusion

  • References