Chapter 37. Atrial Fibrillation: Antithrombotic Therapy

  1. Salim Yusuf DPhil, FRCPC, FRSC Research Chair Professor of Medicine Director Vice President Research2,3,4,
  2. John A Cairns MD, FRCPC Professor of Medicine Former Dean5,
  3. A John Camm MD British Heart Foundation Professor Head of Cardiac6,
  4. Ernest L Fallen MD, FRCPC Professor Emeritus7 and
  5. Bernard J Gersh MB, ChB, DPhil Consultant Professor of Medicine8
  1. John A Cairns MD, FRCPC Professor of Medicine Former Dean5 and
  2. Stuart Connolly MD, FRCPC Director1

Published Online: 21 MAY 2010

DOI: 10.1002/9781444309768.ch37

Evidence-Based Cardiology, Third Edition

Evidence-Based Cardiology, Third Edition

How to Cite

Cairns, J. A. and Connolly, S. (2009) Atrial Fibrillation: Antithrombotic Therapy, in Evidence-Based Cardiology, Third Edition (eds S. Yusuf, J. A. Cairns, A. J. Camm, E. L. Fallen and B. J. Gersh), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444309768.ch37

Editor Information

  1. 2

    McMaster University, Canada

  2. 3

    Population Health Research Institute, McMaster University, Hamilton Health Sciences, Canada

  3. 4

    Hamilton Health Sciences, Hamilton, Ontario, Canada

  4. 5

    Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada

  5. 6

    St George's University of London, London, UK

  6. 7

    McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

  7. 8

    Mayo Clinic College of Medicine, Rochester, MN, USA

Author Information

  1. 1

    McMaster University, Hamilton, Ontario, Canada

  2. 5

    Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada

Publication History

  1. Published Online: 21 MAY 2010
  2. Published Print: 13 NOV 2009

ISBN Information

Print ISBN: 9781405159258

Online ISBN: 9781444309768

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Keywords:

  • atrial fibrillation - antithrombotic therapy;
  • definitions, incidence and natural history - stroke and non-central nervous system (CNS) embolism;
  • antithrombotic management - oral anticoagulant therapy;
  • risk stratification - stroke or systemic embolus;
  • rate versus rhythm control;
  • atrial fibrillation and coronary artery disease;
  • interruption of warfarin therapy in relation to surgical procedures

Summary

This chapter contains sections titled:

  • Definitions, incidence and natural history

  • Antithrombotic management

  • Risk stratification (stroke or systemic embolus)

  • Rate versus rhythm control

  • Choice of antithrombotic therapy

  • Cardioversion

  • Atrial flutter

  • Atrial fibrillation and coronary artery disease

  • Interruption of warfarin therapy in relation to surgical procedures

  • Conclusion and recommendations

  • References