Chapter 44. Arrhythmias Due to Monogenic Disorders

  1. Salim Yusuf DPhil, FRCPC, FRSC Research Chair Professor of Medicine Director Vice President Research4,5,6,
  2. John A Cairns MD, FRCPC Professor of Medicine Former Dean7,
  3. A John Camm MD British Heart Foundation Professor Head of Cardiac8,
  4. Ernest L Fallen MD, FRCPC Professor Emeritus9 and
  5. Bernard J Gersh MB, ChB, DPhil Consultant Professor of Medicine10
  1. Dawood Darbar MBChB, MD, FACC Associate Professor Director1,
  2. Prince Kannankeril MD, MSCI Assistant Professor2 and
  3. Dan M L Roden MD Professor Director Assistant Vice-Chancellor3

Published Online: 21 MAY 2010

DOI: 10.1002/9781444309768.ch44

Evidence-Based Cardiology, Third Edition

Evidence-Based Cardiology, Third Edition

How to Cite

Darbar, D., Kannankeril, P. and Roden, D. M. L. (2009) Arrhythmias Due to Monogenic Disorders, in Evidence-Based Cardiology, Third Edition (eds S. Yusuf, J. A. Cairns, A. J. Camm, E. L. Fallen and B. J. Gersh), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444309768.ch44

Editor Information

  1. 4

    McMaster University, Canada

  2. 5

    Population Health Research Institute, McMaster University, Hamilton Health Sciences, Canada

  3. 6

    Hamilton Health Sciences, Hamilton, Ontario, Canada

  4. 7

    Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada

  5. 8

    St George's University of London, London, UK

  6. 9

    McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

  7. 10

    Mayo Clinic College of Medicine, Rochester, MN, USA

Author Information

  1. 1

    Departments of Medicine and Pharmacology, Vanderbilt Arrhythmia Service, Vanderbilt University School of Medicine, Nashville, TN, USA

  2. 2

    Vanderbilt, Department of Pediatrics, University Medical Centre, Nashville, TN, USA

  3. 3

    Departments of Medicine and Pharmacology, Oates Institute, Personalized Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA

Publication History

  1. Published Online: 21 MAY 2010
  2. Published Print: 13 NOV 2009

ISBN Information

Print ISBN: 9781405159258

Online ISBN: 9781444309768



  • arrhythmias due to monogenic disorders;
  • monogenic arrhythmia syndromes - learning from genetics;
  • complexity beyond monogenic arrhythmia disorders;
  • atrial fibrillation (AF) - common cardiac arrhythmia in clinical practice;
  • atrial flutter - association with later stages of congenital heart disease (CHD);
  • other atrial arrhythmias - myocardial disease association;
  • ventricular arrhythmias - congenital long QT syndromes


This chapter contains sections titled:

  • Introduction

  • What we have learned from the genetics of monogenic arrhythmia syndromes

  • Complexity beyond monogenic arrhythmia disorders

  • Atrial fibrillation

  • Atrial flutter

  • Sinus nodal failure

  • Other atrial arrhythmias

  • Ventricular arrhythmias

  • Conclusion

  • References