Chapter 53. Rheumatic Heart Disease: Prevention and Acute Treatment

  1. Salim Yusuf DPhil, FRCPC, FRSC Research Chair Professor of Medicine Director Vice President Research3,4,5,
  2. John A Cairns MD, FRCPC Professor of Medicine Former Dean6,
  3. A John Camm MD British Heart Foundation Professor Head of Cardiac7,
  4. Ernest L Fallen MD, FRCPC Professor Emeritus8 and
  5. Bernard J Gersh MB, ChB, DPhil Consultant Professor of Medicine9
  1. Bongani M Mayosi DPhil, FCP(SA) Professor1 and
  2. Patrick J Commerford MD2

Published Online: 21 MAY 2010

DOI: 10.1002/9781444309768.ch53

Evidence-Based Cardiology, Third Edition

Evidence-Based Cardiology, Third Edition

How to Cite

Mayosi, B. M. and Commerford, P. J. (2009) Rheumatic Heart Disease: Prevention and Acute Treatment, in Evidence-Based Cardiology, Third Edition (eds S. Yusuf, J. A. Cairns, A. J. Camm, E. L. Fallen and B. J. Gersh), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444309768.ch53

Editor Information

  1. 3

    McMaster University, Canada

  2. 4

    Population Health Research Institute, McMaster University, Hamilton Health Sciences, Canada

  3. 5

    Hamilton Health Sciences, Hamilton, Ontario, Canada

  4. 6

    Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada

  5. 7

    St George's University of London, London, UK

  6. 8

    McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

  7. 9

    Mayo Clinic College of Medicine, Rochester, MN, USA

Author Information

  1. 1

    Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa

  2. 2

    Cardiac Clinic, Department of Medicine, University of Cape Town, Groote Schuur Hospital, Cape Town, South Africa

Publication History

  1. Published Online: 21 MAY 2010
  2. Published Print: 13 NOV 2009

ISBN Information

Print ISBN: 9781405159258

Online ISBN: 9781444309768



  • specific cardiovascular disorders - valvular heart disease;
  • rheumatic heart disease - prevention and acute treatment;
  • epidemiology - decrease in rheumatic fever preceding introduction of antibiotics;
  • pathogenesis - causative role of untreated GAS pharyngitis in rheumatic fever;
  • clinical features - clinical criteria first formulated by Duckett Jones (1944);
  • prevention - primary prevention or prevention of recurrent attacks;
  • acute management - suppressing inflammatory response


This chapter contains sections titled:

  • Introduction

  • Epidemiology

  • Pathogenesis

  • Clinical features

  • Prevention

  • Acute management

  • Conclusion

  • References