Chapter 61. Stroke

  1. Salim Yusuf DPhil, FRCPC, FRSC Research Chair Professor of Medicine Director Vice President Research4,5,6,
  2. John A Cairns MD, FRCPC Professor of Medicine Former Dean7,
  3. A John Camm MD British Heart Foundation Professor Head of Cardiac8,
  4. Ernest L Fallen MD, FRCPC Professor Emeritus9 and
  5. Bernard J Gersh MB, ChB, DPhil Consultant Professor of Medicine10
  1. Brian H Buck MD, MSc, FRCPC Assistant Professor1,
  2. Ashfaq Shuaib MD, FRCPC, FAHA Professor Director2 and
  3. Craig Anderson MBBS, PhD, FRACP, FAFPHM Director Professor3

Published Online: 21 MAY 2010

DOI: 10.1002/9781444309768.ch61

Evidence-Based Cardiology, Third Edition

Evidence-Based Cardiology, Third Edition

How to Cite

Buck, B. H., Shuaib, A. and Anderson, C. (2009) Stroke, in Evidence-Based Cardiology, Third Edition (eds S. Yusuf, J. A. Cairns, A. J. Camm, E. L. Fallen and B. J. Gersh), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444309768.ch61

Editor Information

  1. 4

    McMaster University, Canada

  2. 5

    Population Health Research Institute, McMaster University, Hamilton Health Sciences, Canada

  3. 6

    Hamilton Health Sciences, Hamilton, Ontario, Canada

  4. 7

    Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada

  5. 8

    St George's University of London, London, UK

  6. 9

    McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

  7. 10

    Mayo Clinic College of Medicine, Rochester, MN, USA

Author Information

  1. 1

    Division of Neurology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

  2. 2

    Stroke Program, University of Alberta, Edmonton, Alberta, Canada

  3. 3

    Neurological and Mental Health Division, Stroke Medicine and Clinical Neuroscience, The George Institute for International Health, University of Sydney and the Royal Prince Alfred Hospital, Sydney, Australia

Publication History

  1. Published Online: 21 MAY 2010
  2. Published Print: 13 NOV 2009

ISBN Information

Print ISBN: 9781405159258

Online ISBN: 9781444309768



  • specific cardiovascular disorders, others - stroke;
  • hemorrhagic and ischemic strokes;
  • stroke early diagnosis - specialized magnetic resonance imaging (MRI);
  • TOAST - Trial of Org 10172 in Acute Stroke Treatment;
  • AIS - acute ischemic stroke;
  • AIS treatment - intravenous tissue plasminogen activator (tPA) infusion;
  • low molecular weight heparin (LMWH) - recurrent stroke rate reduction;
  • stroke care units (SCU) - stroke patients' outcomes improvement;
  • stroke secondary prevention - medical and surgical stratergies;
  • stroke and transient ischemic attack diagnosis


This chapter contains sections titled:

  • Introduction

  • Acute stroke management

  • Preventing early complications

  • Conclusion

  • Diagnosis of stroke and transient ischemic attack

  • Blood pressure-lowering therapy

  • Antiplatelet therapy

  • Anticoagulation

  • Cholesterol-lowering therapy

  • Carotid revascularization

  • Conclusion

  • References