Chapter 65. Peripheral Arterial Disease

  1. Salim Yusuf DPhil, FRCPC, FRSC Research Chair Professor of Medicine Director Vice President Research2,3,4,
  2. John A Cairns MD, FRCPC Professor of Medicine Former Dean5,
  3. A John Camm MD British Heart Foundation Professor Head of Cardiac6,
  4. Ernest L Fallen MD, FRCPC Professor Emeritus7 and
  5. Bernard J Gersh MB, ChB, DPhil Consultant Professor of Medicine8
  1. Catherine McGorrian MB, BCh, BAO, MRCPI Clinical Fellow and
  2. Sonia S Anand MD, PhD, FRCPC Professor

Published Online: 21 MAY 2010

DOI: 10.1002/9781444309768.ch65

Evidence-Based Cardiology, Third Edition

Evidence-Based Cardiology, Third Edition

How to Cite

McGorrian, C. and Anand, S. S. (2009) Peripheral Arterial Disease, in Evidence-Based Cardiology, Third Edition (eds S. Yusuf, J. A. Cairns, A. J. Camm, E. L. Fallen and B. J. Gersh), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444309768.ch65

Editor Information

  1. 2

    McMaster University, Canada

  2. 3

    Population Health Research Institute, McMaster University, Hamilton Health Sciences, Canada

  3. 4

    Hamilton Health Sciences, Hamilton, Ontario, Canada

  4. 5

    Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada

  5. 6

    St George's University of London, London, UK

  6. 7

    McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

  7. 8

    Mayo Clinic College of Medicine, Rochester, MN, USA

Author Information

  1. Department of Medicine, McMaster University, Hamilton, Ontario, Canada

Publication History

  1. Published Online: 21 MAY 2010
  2. Published Print: 13 NOV 2009

ISBN Information

Print ISBN: 9781405159258

Online ISBN: 9781444309768



  • peripheral arterial disease (PAD);
  • PAD - arterial disease, - affecting arterial vasculature outside heart;
  • PAD prevalence - age and diagnosis method;
  • PAD risk factors - tobacco exposure, hypertension;
  • Ankle Brachial Index (ABI) - PAD diagnosis;
  • PD therapies - lifestyle measures;
  • nicotine replacement therapy (NRT) - smoking ceassation


This chapter contains sections titled:

  • Introduction

  • Epidemiology and natural history

  • Risk factors

  • Diagnosis

  • Therapeutics

  • Special considerations: critical limb ischemia and acute limb ischemia

  • Conclusion

  • References