Chapter 11. Transfusion-Associated Graft-Versus-Host Disease and Microchimerism

  1. Michael F. Murphy MD, FRCP, FRCPath Professor Consultant Haematologist4,5 and
  2. Derwood H. Pamphilon MD, MRCPCH, FRCP, FRCPath Consultant Haematologist Honorary Clinical Reader6,7
  1. Beth H. Shaz MD Director Assistant Professor1,2 and
  2. Christopher D. Hillyer MD Director Professor2,3

Published Online: 5 MAY 2009

DOI: 10.1002/9781444311761.ch11

Practical Transfusion Medicine, Third Edition

Practical Transfusion Medicine, Third Edition

How to Cite

Shaz, B. H. and Hillyer, C. D. (2009) Transfusion-Associated Graft-Versus-Host Disease and Microchimerism, in Practical Transfusion Medicine, Third Edition (eds M. F. Murphy and D. H. Pamphilon), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444311761.ch11

Editor Information

  1. 4

    University of Oxford, Oxford, UK

  2. 5

    NHS Blood and Transplant and Department of Haematology, John Radcliffe Hospital, Oxford, UK

  3. 6

    NHS Blood and Transplant, Bristol, UK

  4. 7

    Department of Cellular and Molecular Medicine, University of Bristol, Bristol, UK

Author Information

  1. 1

    Grady Memorial Hospital, Atlanta, Georgia, USA

  2. 2

    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA

  3. 3

    Center for Transfusion and Cellular Therapies, Atlanta, Georgia, USA

Publication History

  1. Published Online: 5 MAY 2009
  2. Published Print: 14 APR 2009

ISBN Information

Print ISBN: 9781405181969

Online ISBN: 9781444311761



  • transfusion-associated graft-versus-host disease (TA-GVHD);
  • lymphocytes;
  • erythematous maculopapular rash;
  • polymerase chain reaction (PCR);
  • adverse effects of irradiation;
  • extracellular potassium;
  • Hodgkin's disease (HD);
  • haemovigilance;
  • microchimerism (MC)


This chapter contains sections titled:

  • Transfusion-associated graft-versus-host disease

  • Transfusion-associated microchimerism

  • Key points

  • Further reading