Chapter 41. Cord Blood Transplantation

  1. Michael F. Murphy MD, FRCP, FRCPath Professor Consultant Haematologist3,4 and
  2. Derwood H. Pamphilon MD, MRCPCH, FRCP, FRCPath Consultant Haematologist Honorary Clinical Reader5,6
  1. Leandro de Padua Silva MD Postdoctoral Fellow1,
  2. Marcos de Lima MD Associate Professor1,
  3. Elizabeth J. Shpall MD Professor Director2 and
  4. Susan Armitage BSc Assistant Director2

Published Online: 5 MAY 2009

DOI: 10.1002/9781444311761.ch41

Practical Transfusion Medicine, Third Edition

Practical Transfusion Medicine, Third Edition

How to Cite

de Padua Silva, L., de Lima, M., Shpall, E. J. and Armitage, S. (2009) Cord Blood Transplantation, in Practical Transfusion Medicine, Third Edition (eds M. F. Murphy and D. H. Pamphilon), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444311761.ch41

Editor Information

  1. 3

    University of Oxford, Oxford, UK

  2. 4

    NHS Blood and Transplant and Department of Haematology, John Radcliffe Hospital, Oxford, UK

  3. 5

    NHS Blood and Transplant, Bristol, UK

  4. 6

    Department of Cellular and Molecular Medicine, University of Bristol, Bristol, UK

Author Information

  1. 1

    Department of Stem Cell Transplantation and Cell Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

  2. 2

    Cord Blood Bank, Department of Stem Cell Transplantation and Cell Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Publication History

  1. Published Online: 5 MAY 2009
  2. Published Print: 14 APR 2009

ISBN Information

Print ISBN: 9781405181969

Online ISBN: 9781444311761

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Keywords:

  • cord blood transplantation;
  • graft-versus-host disease (GVHD);
  • sickle-cell disease;
  • transplant-related mortality (TRM);
  • non-myeloablative setting;
  • leukaemia-free survival (LFS);
  • genetic disorders

Summary

This chapter contains sections titled:

  • Rationale for cord blood transplantation

  • Types of CB banking

  • Advantages of CB as a source of haemopoietic stem cells

  • Disadvantages of CB as a source of haemopoietic stem cells

  • Ethics and consent issues of CB banking

  • Operation of CB banking

  • Clinical results of CB transplantation

  • Future directions

  • Summary

  • Key Points

  • Further reading