Chapter 7. Haemolytic Transfusion Reactions

  1. Michael F. Murphy MD, FRCP, FRCPath Professor Consultant Haematologist2,3 and
  2. Derwood H. Pamphilon MD, MRCPCH, FRCP, FRCPath Consultant Haematologist Honorary Clinical Reader4,5
  1. Edwin Massey MB ChB, FRCP, FRCPath Consultant Haematologist4 and
  2. Geoff Poole DBMS, MSc, CSci, FIBMS Director1

Published Online: 5 MAY 2009

DOI: 10.1002/9781444311761.ch7

Practical Transfusion Medicine, Third Edition

Practical Transfusion Medicine, Third Edition

How to Cite

Massey, E. and Poole, G. (2009) Haemolytic Transfusion Reactions, in Practical Transfusion Medicine, Third Edition (eds M. F. Murphy and D. H. Pamphilon), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444311761.ch7

Editor Information

  1. 2

    University of Oxford, Oxford, UK

  2. 3

    NHS Blood and Transplant and Department of Haematology, John Radcliffe Hospital, Oxford, UK

  3. 4

    NHS Blood and Transplant, Bristol, UK

  4. 5

    Department of Cellular and Molecular Medicine, University of Bristol, Bristol, UK

Author Information

  1. 1

    Welsh Blood Service, Bridgend, Wales, UK

  2. 4

    NHS Blood and Transplant, Bristol, UK

Publication History

  1. Published Online: 5 MAY 2009
  2. Published Print: 14 APR 2009

ISBN Information

Print ISBN: 9781405181969

Online ISBN: 9781444311761

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Keywords:

  • haemolytic transfusion reaction (HTR);
  • intravascular haemolysis;
  • antibody-mediated intravascular haemolysis;
  • membrane attack complex (MAC);
  • cytokines;
  • acute HTRs;
  • solid organ transplants;
  • haemolytic syndrome;
  • sickle-cell anaemia

Summary

This chapter contains sections titled:

  • Pathophysiology of HTRs

  • Acute HTRs

  • Delayed HTRs

  • Key points

  • Further reading