Chapter 5. Genomics and Atrial Arrhythmias

  1. Dan Roden MD Professor Director Assistant Vice-Chancellor
  1. Dawood Darbar MD Associate Professor1 and
  2. Calum A. MacRae MD2

Published Online: 27 APR 2009

DOI: 10.1002/9781444311785.ch5

Cardiovascular Genetics and Genomics

Cardiovascular Genetics and Genomics

How to Cite

Darbar, D. and MacRae, C. A. (2009) Genomics and Atrial Arrhythmias, in Cardiovascular Genetics and Genomics (ed D. Roden), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444311785.ch5

Editor Information

  1. Oates Institute for Experimental Therapeutics, Personalized Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA

Author Information

  1. 1

    Direct, Vanelerbilt Arrhythnia Service, Vanderbilt University School of Medicine, Nashville, TN, USA

  2. 2

    Cardiovascular Division and Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

Publication History

  1. Published Online: 27 APR 2009
  2. Published Print: 17 APR 2009

Book Series:

  1. The AHA Clinical Series

Book Series Editors:

  1. Elliott Antman

ISBN Information

Print ISBN: 9781405175401

Online ISBN: 9781444311785



  • genomics and atrial arrhythmias;
  • Atrial fibrillation (AF);
  • long QT syndrome (LQTS);
  • cardiac monogenic disorders;
  • renin–angiotensin–aldosterone (RAAS) activation;
  • positional cloning strategy;
  • paroxysmal nature;
  • pulmonary venous anatomy;
  • congenital heart disease (CHD)


This chapter contains sections titled:

  • Introduction

  • Atrial fibrillation

  • Uncovering common genes for atrial fibrillation

  • Novel genetic mechanisms

  • Atrial flutter

  • Sinus nodal failure

  • Other atrial arrhythmias

  • Pharmacogenomics

  • Future directions

  • References