Chapter 26. Pathology of the Liver Allograft

  1. Richard N. Fine MD Dean Distinguished Professor of Pediatrics3,
  2. Steven A. Webber MBChB, MRCP Professor of Pediatrics4,
  3. Kim M. Olthoff MD, FACS Associate Professor of Surgery Director5,
  4. Deirdre A. Kelly MD, FRCPI, FRCP, FRCPCH Professor of Paediatric Hepatology6 and
  5. William E. Harmon MD Professor of Pediatrics7
  1. Maria Parizhskaya MD1 and
  2. Ronald Jaffe MB.BCh Professor of Pathology2

Published Online: 5 MAY 2009

DOI: 10.1002/9781444312720.ch26

Pediatric Solid Organ Transplantation, Second Edition

Pediatric Solid Organ Transplantation, Second Edition

How to Cite

Parizhskaya, M. and Jaffe, R. (2009) Pathology of the Liver Allograft, in Pediatric Solid Organ Transplantation, Second Edition (eds R. N. Fine, S. A. Webber, K. M. Olthoff, D. A. Kelly and W. E. Harmon), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444312720.ch26

Editor Information

  1. 3

    Stony Brook University School of Medicine, Stony Brook, New York 11794-8111, USA

  2. 4

    University of Pittsburgh School of Medicine, Division of Cardiology, Children's Hospital, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA

  3. 5

    Liver Transplant Program, University of Pennsylvania and the Children's Hospital of Philadelphia, 2 Dulles, 3400 Spruce Street, Philadelphia, PA 19104, USA

  4. 6

    The Liver Unit, Birmingham Children's Hospital NHS Trust, Steelhouse Lane, Birmingham, B4 6NH, UK

  5. 7

    Division of Nephrology, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Hunn-319, Boston, MA 02115, USA

Author Information

  1. 1

    Pathologist, Virginia Beach, VA, USA

  2. 2

    University of Pittsburgh School of Medicine, Marjory K. Harmer Professor of Pediatric Pathology, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA

Publication History

  1. Published Online: 5 MAY 2009
  2. Published Print: 24 JAN 2007

ISBN Information

Print ISBN: 9781405124072

Online ISBN: 9781444312720



  • therapeutic drug monitoring;
  • clinical suspicion of cholangitis;
  • primary allograft failure;
  • hepatocellular necrosis;
  • vascular disorders;
  • bile ductular proliferation;
  • acute cellular rejection;
  • mononuclear infiltrates;
  • active viral replication


This chapter contains sections titled:

  • Donor Evaluation

  • Handling of Allograft Liver Tissues

  • Primary Allograft Failure

  • Harvesting-Related Injury

  • Vascular Disorders

  • Biliary Disorders

  • Acute Cellular Rejection

  • Chronic Rejection

  • Infections

  • Post-Transplant Lymphoproliferative Disease

  • EBV-Related Smooth Muscle Tumor

  • Drug Reactions

  • Recurrence of Primary Disease in the Allograft

  • References