Chapter 4. Morphologic Evolution of Hepatocellular Carcinoma: From Early to Advanced

  1. Masamichi Kojiro MD

Published Online: 29 APR 2009

DOI: 10.1002/9781444312775.ch4

Pathology of Hepatocellular Carcinoma

Pathology of Hepatocellular Carcinoma

How to Cite

Kojiro, M. (2006) Morphologic Evolution of Hepatocellular Carcinoma: From Early to Advanced, in Pathology of Hepatocellular Carcinoma, Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444312775.ch4

Author Information

  1. Department of Pathology, Kurume University School of Medicine, Kurume, Japan

Publication History

  1. Published Online: 29 APR 2009
  2. Published Print: 4 SEP 2006

ISBN Information

Print ISBN: 9781405139083

Online ISBN: 9781444312775

SEARCH

Keywords:

  • morphologic evolution of hepatocellular carcinoma: from early to advanced;
  • slow-growing hepatoma;
  • transforming growth factor;
  • beta-catenin;
  • p53 protein;
  • clonal dedifferentiation of early-stage HCC

Summary

This chapter contains sections titled:

  • Dedifferentiation and proliferation in well-differentiated HCC

  • Slow-growing hepatoma

  • A “nodule-in-nodule” appearance

  • Mechanism of dedifferentiation of well-differentiated HCC

  • Clonal dedifferentiation of early-stage HCC

  • References