Chapter 6. Advanced Hepatocellular Carcinoma

  1. Masamichi Kojiro MD

Published Online: 29 APR 2009

DOI: 10.1002/9781444312775.ch6

Pathology of Hepatocellular Carcinoma

Pathology of Hepatocellular Carcinoma

How to Cite

Kojiro, M. (2006) Advanced Hepatocellular Carcinoma, in Pathology of Hepatocellular Carcinoma, Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444312775.ch6

Author Information

  1. Department of Pathology, Kurume University School of Medicine, Kurume, Japan

Publication History

  1. Published Online: 29 APR 2009
  2. Published Print: 4 SEP 2006

ISBN Information

Print ISBN: 9781405139083

Online ISBN: 9781444312775



  • advanced hepatocellular carcinoma;
  • fibrous capsule and septa;
  • mechanism of capsule formation;
  • pedunculated HCC;
  • architectural patterns – trabecular pattern, pseudoglandular and acinar patterns, compact (solid) pattern;
  • intracytoplasmic inclusions – hyaline bodies, pale bodies


This chapter contains sections titled:

  • Gross findings

  • Gross classification

  • Histologic features of advanced HCC

  • HCC of variant type

  • Unusual tumor growth in HCC

  • Extrahepatic metastasis

  • References