Chapter 20. Transfer Factor (Diffusing Capacity) for Carbon Monoxide and Nitric Oxide (Tl,CO, Tl,NO, Dm and VC)

  1. J. E. Cotes DM, DSc (Oxon), FRCP, FFOM, Dhc Visitor Reader in Respiratory Physiology External Scientific Staff of Medical Research Council Honorary Consultant in Clinical Respiratory Physiology1,
  2. D. J. Chinn BSc, PhD, MSc (Public Health) Senior Research Fellow in Epidemiology2,† and
  3. M. R. Miller BSc, MD, FRCP Consultant Respiratory Physician3

Published Online: 30 APR 2009

DOI: 10.1002/9781444312829.ch20

Lung Function: Physiology, Measurement and Application in Medicine, Sixth Edition

Lung Function: Physiology, Measurement and Application in Medicine, Sixth Edition

How to Cite

Cotes, J. E., Chinn, D. J. and Miller, M. R. (2006) Transfer Factor (Diffusing Capacity) for Carbon Monoxide and Nitric Oxide (Tl,CO, Tl,NO, Dm and VC), in Lung Function: Physiology, Measurement and Application in Medicine, Sixth Edition, Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444312829.ch20

Author Information

  1. 1

    University Department of Physiological Sciences, Newcastle upon Tyne, UK

  2. 2

    Centre for Primary and Community Care, University of Sunderland, Sunderland, UK

  3. 3

    University Hospital Birmingham NHS Trust, Birmingham, UK

  1. Senior Research Fellow, School of Clinical Sciences and Community Health, University of Edinburgh, UK

Publication History

  1. Published Online: 30 APR 2009
  2. Published Print: 20 MAR 2006

ISBN Information

Print ISBN: 9780632064939

Online ISBN: 9781444312829

SEARCH

Keywords:

  • measurement of transfer factor (diffusing capacity) for carbon monoxide (Tl,CO) and its subdivisions;
  • measurement of Tl,CO (steady state method);
  • measuring Tl,CO (single breath / breath-holding method);
  • measuring Tl,CO (rebreathing method / intra-breath method);
  • contributions of haemoglobin and tensions of O2 and CO;
  • measurement of Dm and VC (Roughton–Forster method);
  • interpretation of Tl,CO and related indices

Summary

This chapter contains sections titled:

  • Introduction

  • Methods for measuring Tl,CO

  • Measurement of Tl,CO.ss (steady state method)

  • Measurement of Tl,CO.sb (single breath, breath-holding method)

  • Measurement of Tl,CO.rb (rebreathing method)

  • Measurement of Tl,CO.ib (intra-breath method)

  • Contributions of haemoglobin and tensions of O2 and CO

  • Measurement of Dm and VC (Roughton–Forster method)

  • Interpretation of Tl,CO and related indices

  • Measurement of Tl,NO (transfer factor for nitric oxide)

  • References

  • Further reading