22. Headache

  1. Catherine F. Stannard MB ChB, FRCA, FFPMRCA,
  2. Eija Kalso MD, DMedSci and
  3. Jane Ballantyne MD
  1. Peer Tfelt-Hansen MD, DMSc

Published Online: 20 JUN 2010

DOI: 10.1002/9781444314380.ch22

Evidence-Based Chronic Pain Management

Evidence-Based Chronic Pain Management

How to Cite

Tfelt-Hansen, P. (2010) Headache, in Evidence-Based Chronic Pain Management (eds C. F. Stannard, E. Kalso and J. Ballantyne), John Wiley & Sons, Ltd., West Sussex, UK. doi: 10.1002/9781444314380.ch22

Author Information

  1. Danish Headache Centre, Department of Neurology, University of Copenhagen, Glostrup Hospital, Glostrup, Denmark

Publication History

  1. Published Online: 20 JUN 2010
  2. Published Print: 5 MAR 2010

ISBN Information

Print ISBN: 9781405152914

Online ISBN: 9781444314380



  • headache;
  • primary headaches;
  • pain character, severity and location in primary headaches;
  • NO donor glyceryl trinitrate (GTN);
  • calcitonin gene-related peptide (CGRP) in external jugular during migraine attacks;
  • tension-type headache;
  • cluster headache, chronobiologic headache with attacks occurring;
  • tension-type headaches - emotional conflict and psychosocial stress;
  • increased tenderness in pericranial muscles - in patients with tension-type headache


This chapter contains sections titled:

  • Introduction

  • Primary headaches

  • Pathophysiology

  • Systematic reviews and meta-analyses in migraine

  • Clinical trials in tension-type headache

  • Clinical trials in cluster headache

  • Research needed to improve the evidence-based management of migraine

  • References