10. Celiac Disease: Diagnosis, Treatment and Prognosis

  1. John WD McDonald Professor of Medicine2,
  2. Andrew K Burroughs Professor of Hepatology Consultant Physician/Hepatologist3,
  3. Brian G Feagan Professor of Medicine2 and
  4. M Brian Fennerty Professor of Medicine4
  1. James Gregor and
  2. Michael Sai Lai Sey

Published Online: 22 JUL 2010

DOI: 10.1002/9781444314403.ch10

Evidence-Based Gastroenterology and Hepatology, Third Edition

Evidence-Based Gastroenterology and Hepatology, Third Edition

How to Cite

Gregor, J. and Sey, M. S. L. (2010) Celiac Disease: Diagnosis, Treatment and Prognosis, in Evidence-Based Gastroenterology and Hepatology, Third Edition (eds J. W. McDonald, A. K. Burroughs, B. G. Feagan and M. B. Fennerty), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444314403.ch10

Editor Information

  1. 2

    Robarts Clinical Trials, Robarts Research Unit, University of Western Ontario, London, Ontario, Canada

  2. 3

    The Royal Free Sheila Sherlock Liver Centre, Royal Free Hospital, and University College London, London, UK

  3. 4

    Oregon Health and Science University, Division of Gastroenterology and Hepatology, Portland, Oregon, USA

Author Information

  1. Department of Medicine, University of Western Ontario, London, Ontario, Canada

Publication History

  1. Published Online: 22 JUL 2010
  2. Published Print: 10 SEP 2010

ISBN Information

Print ISBN: 9781405181938

Online ISBN: 9781444314403

SEARCH

Keywords:

  • Celiac disease: Diagnosis, treatment and prognosis;
  • “prolamins”, produces both clinical symptoms and histological lesions;
  • tissue transglutaminase (tTG);
  • autoimmune response is the tTG brush border enzyme;
  • antireticulin antibodies (ARA);
  • antigliadin antibodies (AGA);
  • anti-smooth muscle endomysium antibodies (EMA);
  • anti-tissue transglutaminase antibodies (tTG);
  • Since tTG assays utilize ELISA, they offer several advantages over conventional immunofluorscence based EMA;
  • celiac patients to a conventional gluten free diet (GFD) versus

Summary

This chapter contains sections titled:

  • Epidemiology

  • Clinical manifestations

  • Pathology

  • Serological testing

  • Therapy

  • Prognosis

  • Conclusion

  • References