15. Drug-Induced Diarrhea

  1. John WD McDonald Professor of Medicine2,
  2. Andrew K Burroughs Professor of Hepatology Consultant Physician/Hepatologist3,
  3. Brian G Feagan Professor of Medicine2 and
  4. M Brian Fennerty Professor of Medicine4
  1. Bincy P Abraham and
  2. Joseph H Sellin

Published Online: 22 JUL 2010

DOI: 10.1002/9781444314403.ch15

Evidence-Based Gastroenterology and Hepatology, Third Edition

Evidence-Based Gastroenterology and Hepatology, Third Edition

How to Cite

Abraham, B. P. and Sellin, J. H. (2010) Drug-Induced Diarrhea, in Evidence-Based Gastroenterology and Hepatology, Third Edition (eds J. W. McDonald, A. K. Burroughs, B. G. Feagan and M. B. Fennerty), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444314403.ch15

Editor Information

  1. 2

    Robarts Clinical Trials, Robarts Research Unit, University of Western Ontario, London, Ontario, Canada

  2. 3

    The Royal Free Sheila Sherlock Liver Centre, Royal Free Hospital, and University College London, London, UK

  3. 4

    Oregon Health and Science University, Division of Gastroenterology and Hepatology, Portland, Oregon, USA

Author Information

  1. Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, USA

Publication History

  1. Published Online: 22 JUL 2010
  2. Published Print: 10 SEP 2010

ISBN Information

Print ISBN: 9781405181938

Online ISBN: 9781444314403



  • Drug-induced diarrhea;
  • randomized controlled trials (RCTs);
  • significant increase in stool volume would both be labeled “diarrhea”;
  • prebiotics fructo-oligosaccharides and inulins;
  • rise in intracellular cyclic AMP levels;
  • Disordered or deregulation motility;
  • non-steroidal anti-inflammatory drugs (NSAIDs);
  • the specificity of steatorrhea secondary to HAART may be called into question


This chapter contains sections titled:

  • Drug induced diarrhea

  • Watery diarrhea

  • Inflammatory diarrhea

  • Fatty diarrhea

  • Conclusion

  • References