35. Non-Histological Assessment of Liver Fibrosis

  1. John WD McDonald Professor of Medicine2,
  2. Andrew K Burroughs Professor of Hepatology Consultant Physician/Hepatologist3,
  3. Brian G Feagan Professor of Medicine2 and
  4. M Brian Fennerty Professor of Medicine4
  1. Dominique Thabut and
  2. Marika Simon-Rudler

Published Online: 22 JUL 2010

DOI: 10.1002/9781444314403.ch35

Evidence-Based Gastroenterology and Hepatology, Third Edition

Evidence-Based Gastroenterology and Hepatology, Third Edition

How to Cite

Thabut, D. and Simon-Rudler, M. (2010) Non-Histological Assessment of Liver Fibrosis, in Evidence-Based Gastroenterology and Hepatology, Third Edition (eds J. W. McDonald, A. K. Burroughs, B. G. Feagan and M. B. Fennerty), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444314403.ch35

Editor Information

  1. 2

    Robarts Clinical Trials, Robarts Research Unit, University of Western Ontario, London, Ontario, Canada

  2. 3

    The Royal Free Sheila Sherlock Liver Centre, Royal Free Hospital, and University College London, London, UK

  3. 4

    Oregon Health and Science University, Division of Gastroenterology and Hepatology, Portland, Oregon, USA

Author Information

  1. UPMC Service d'Hépato-Gastroentérologie, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Université Pierre et Marie Curie, Paris, France

Publication History

  1. Published Online: 22 JUL 2010
  2. Published Print: 10 SEP 2010

ISBN Information

Print ISBN: 9781405181938

Online ISBN: 9781444314403

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Keywords:

  • Serum markers of liver fibrosis;
  • Diagnostic performance of the different serum markers of fibrosis;
  • Is there a way to optimize the performance of the tests?;
  • Can we expect more from non-invasive tests?;
  • Correlation with clinical events and survival;
  • Proposed algorithm for the prediction of liver fibrosis in HCV patients;
  • Non-histological assessment of liver fibrosis;
  • metalloproteases (MMPs);
  • tissue inhibitors of metalloproteases (TIMPs);
  • Description of the different serum markers and indices

Summary

This chapter contains sections titled:

  • Serum markers of liver fibrosis

  • Transient elastography

  • Is there a way to optimize the performance of the tests?

  • Can we expect more from non-invasive tests?

  • Correlation with clinical events and survival

  • Proposed algorithm for the prediction of liver fibrosis in HCV patients

  • Conclusion

  • References