41. Fulminant Hepatic Failure: Treatment

  1. John WD McDonald Professor of Medicine5,
  2. Andrew K Burroughs Professor of Hepatology Consultant Physician/Hepatologist6,
  3. Brian G Feagan Professor of Medicine5 and
  4. M Brian Fennerty Professor of Medicine7
  1. James O'Beirne1,
  2. Nicholas Murphy2 and
  3. Julia Wendon3,4

Published Online: 22 JUL 2010

DOI: 10.1002/9781444314403.ch41

Evidence-Based Gastroenterology and Hepatology, Third Edition

Evidence-Based Gastroenterology and Hepatology, Third Edition

How to Cite

O'Beirne, J., Murphy, N. and Wendon, J. (2010) Fulminant Hepatic Failure: Treatment, in Evidence-Based Gastroenterology and Hepatology, Third Edition (eds J. W. McDonald, A. K. Burroughs, B. G. Feagan and M. B. Fennerty), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444314403.ch41

Editor Information

  1. 5

    Robarts Clinical Trials, Robarts Research Unit, University of Western Ontario, London, Ontario, Canada

  2. 6

    The Royal Free Sheila Sherlock Liver Centre, Royal Free Hospital, and University College London, London, UK

  3. 7

    Oregon Health and Science University, Division of Gastroenterology and Hepatology, Portland, Oregon, USA

Author Information

  1. 1

    Royal Free Hospital, London, UK

  2. 2

    Queen Elizabeth Hospital (Birmingham), Edgbaston, Birmingham, UK

  3. 3

    King's College London School of Medicine, London, UK

  4. 4

    Liver Intensive Care, King's College Hospital, London, UK

Publication History

  1. Published Online: 22 JUL 2010
  2. Published Print: 10 SEP 2010

ISBN Information

Print ISBN: 9781405181938

Online ISBN: 9781444314403



  • Fulminant hepatic failure: Treatment;
  • fulminant hepatic failure (FHF);
  • Intensive care management versus ward management;
  • orthotopic liver transplantation (OLT);
  • Fluid resuscitation and circulatory management;
  • central venous pressure (CVP);
  • pulmonary artery occlusion pressure (PAOP);
  • stroke volume variation (SVV);
  • pulse pressure variation (PPV);
  • cerebral perfusion pressure (CPP)


This chapter contains sections titled:

  • Introduction

  • General supportive management

  • Management of cerebral edema

  • Renal failure

  • Specific therapies

  • Liver transplantation

  • References