Chapter 6. Poly-L-Lactic Acid

  1. Derek Jones Director Founder Clinical Associate Professor
  1. Rebecca Fitzgerald MD Assistant Clinical Instructor1 and
  2. Danny Vleggaar MD Medical Director2

Published Online: 10 MAR 2010

DOI: 10.1002/9781444315004.ch6

Injectable Fillers: Principles and Practice

Injectable Fillers: Principles and Practice

How to Cite

Fitzgerald, R. and Vleggaar, D. (2010) Poly-L-Lactic Acid, in Injectable Fillers: Principles and Practice (ed D. Jones), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444315004.ch6

Editor Information

  1. David Geffin School of Medicine, University of California, Los Angeles, USA

Author Information

  1. 1

    Dermatology Private Practice, Los Angeles, David Geffen School of Medicine, University of California, Los Angeles, USA

  2. 2

    Centre Dermato - Cosmetique ‘Roseraie’, Geneva, Switzerland

Publication History

  1. Published Online: 10 MAR 2010
  2. Published Print: 31 MAR 2010

ISBN Information

Print ISBN: 9781405192897

Online ISBN: 9781444315004

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Keywords:

  • Poly-l-lactic acid;
  • Sculptra;
  • collagen stimulators;
  • nonsurgical facial rejuvenation;
  • facial shaping;
  • facial volumizing;
  • fillers;
  • aging face;
  • facial analysis;
  • facial augmentation

Summary

Currently recommended preparation and placement techniques using poly-l-lactic acid (PLLA) are discussed in detail. PLLA is not a filler, but a stimulator of the host's own collagen which then acts to volumize tissues in a gradual, progressive manner. This mechanism of action has important clinical implications in the manner in which it is used. Aging occurs in all tissue layers of the face in a gradual, progressive manner, and this process is reflected in new lines and folds over time. As experience has been gained with this product over the last decade, and our techniques adjusted accordingly, we have found it to be a very safe and versatile agent that can replace or mimic the volume lost in multiple tissue layers in a manner that is both predictable and reproducible