Chapter 4. Primary Cutaneous CD30+ Lymphoproliferative Disorders

  1. Lorenzo Cerroni MD Associate Professor of Dermatology1,
  2. Kevin Gatter BM, DPhil, FRCPath Head of Department Professor of Pathology2 and
  3. Helmut Kerl MD Professor Emeritus of Dermatology1

Published Online: 5 MAY 2010

DOI: 10.1002/9781444316742.ch4

Skin Lymphoma: The Illustrated Guide, Third Edition

Skin Lymphoma: The Illustrated Guide, Third Edition

How to Cite

Cerroni, L., Gatter, K. and Kerl, H. (2009) Primary Cutaneous CD30+ Lymphoproliferative Disorders, in Skin Lymphoma: The Illustrated Guide, Third Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444316742.ch4

Author Information

  1. 1

    Medical University of Graz, Graz, Austria

  2. 2

    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK

Publication History

  1. Published Online: 5 MAY 2010
  2. Published Print: 28 AUG 2009

ISBN Information

Print ISBN: 9781405185547

Online ISBN: 9781444316742



  • primary cutaneous CD30+ lymphoproliferative disorders;
  • CD30 antigen, cytokine receptor - tumor necrosis factor receptor superfamily;
  • lymphomatoid papulosis - generalized papules eruption;
  • regional lymphomatoid papulosis - localized lymphomatoid papulosis lesions;
  • lymphomatoid papulosis histopathologic subtypes - A, B, C;
  • lymphomatoid papulosis - neoplastic cells expressing CD30;
  • clinicopathologic differential diagnosis - PLEVA;
  • PLEVA - pityriasis lichenoides et varioliformis acuta;
  • cutaneous anaplastic large cell lymphoma -ulcerated reddish-brown tumors


This chapter contains sections titled:

  • Clinical features

  • Histopathology, immunophenotype and molecular genetics

  • Clinicopathologic differential diagnosis

  • Treatment

  • Prognosis

  • References