Chapter 5. Subcutaneous “Panniculitis-Like” T-Cell Lymphoma

  1. Lorenzo Cerroni MD Associate Professor of Dermatology1,
  2. Kevin Gatter BM, DPhil, FRCPath Head of Department Professor of Pathology2 and
  3. Helmut Kerl MD Professor Emeritus of Dermatology1

Published Online: 5 MAY 2010

DOI: 10.1002/9781444316742.ch5

Skin Lymphoma: The Illustrated Guide, Third Edition

Skin Lymphoma: The Illustrated Guide, Third Edition

How to Cite

Cerroni, L., Gatter, K. and Kerl, H. (2009) Subcutaneous “Panniculitis-Like” T-Cell Lymphoma, in Skin Lymphoma: The Illustrated Guide, Third Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444316742.ch5

Author Information

  1. 1

    Medical University of Graz, Graz, Austria

  2. 2

    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK

Publication History

  1. Published Online: 5 MAY 2010
  2. Published Print: 28 AUG 2009

ISBN Information

Print ISBN: 9781405185547

Online ISBN: 9781444316742



  • subcutaneous “panniculitis-like” T-cell lymphoma;
  • subcutaneous fat and α/β cytotoxic T-cell phenotype involvement;
  • subcutaneous T-cell lymphoma diagnosis - adipocytes rimming by neoplastic lymphocytes;
  • immunohistologic analysis - neoplastic cells α/β T-suppressor phenotype;
  • NK and T-cell lymphomas and subcutaneous tissue involvement;
  • lupus panniculitis - differential diagnosis;
  • hemophagocytic syndrome onset as bad prognostic sign


This chapter contains sections titled:

  • Clinical features

  • Histopathology, immunophenotype and molecular genetics

  • Differential diagnosis with other cutaneous NK and T-cell lymphomas with prominent involvement of the subcutaneous tissue

  • Differential diagnosis with lupus panniculitis

  • Treatment

  • Prognosis

  • References