Chapter 6. Aggressive Cutaneous Cytotoxic Lymphomas

  1. Lorenzo Cerroni MD Associate Professor of Dermatology1,
  2. Kevin Gatter BM, DPhil, FRCPath Head of Department Professor of Pathology2 and
  3. Helmut Kerl MD Professor Emeritus of Dermatology1

Published Online: 5 MAY 2010

DOI: 10.1002/9781444316742.ch6

Skin Lymphoma: The Illustrated Guide, Third Edition

Skin Lymphoma: The Illustrated Guide, Third Edition

How to Cite

Cerroni, L., Gatter, K. and Kerl, H. (2009) Aggressive Cutaneous Cytotoxic Lymphomas, in Skin Lymphoma: The Illustrated Guide, Third Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444316742.ch6

Author Information

  1. 1

    Medical University of Graz, Graz, Austria

  2. 2

    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK

Publication History

  1. Published Online: 5 MAY 2010
  2. Published Print: 28 AUG 2009

ISBN Information

Print ISBN: 9781405185547

Online ISBN: 9781444316742

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Keywords:

  • aggressive cutaneous cytotoxic lymphomas;
  • cytotoxic lymphomas - T or natural killer (NK) lymphocytes derived tumors;
  • primary cutaneous aggressive epidermotropic CD8+ cytotoxic t cell lymphoma;
  • T-cell receptor (TCR) gene monoclonal rearrangement;
  • prognosis - metastasizes to lung, testis;
  • primary cutaneous γ/δ T-cell lymphoma;
  • γ/δ T-cell lymphoma - NK-cell-associated genes overexpression;
  • NK-cell-associated genes - killer cell immunoglobulin-ike receptor (KIR) genes;
  • extranodal NK/T-cell lymphoma - nasal type, cytotoxic lymphoma;
  • NK/T-cell lymphoma - oligoclonal NK cell proliferation

Summary

This chapter contains sections titled:

  • Clinical features

  • Histopathology, immunophenotype and molecular genetics

  • Treatment

  • Prognosis

  • Clinical features, histopathology, immunophenotype and molecular genetics

  • Treatment and prognosis

  • References