Chapter 2. Ion Channels

  1. José Jalife MD Professor of Internal Medicine Professor of Molecular & Integrative Physiology1,2,
  2. Mario Delmar MD, PhD Professor of Internal Medicine3,4,
  3. Justus Anumonwo PhD Assistant Professor of Internal Medicine5,
  4. Omer Berenfeld PhD Assistant Professor of Internal Medicine and Biomedical Engineering5 and
  5. Jérôme Kalifa MD, PhD Assistant Professor of Internal Medicine5

Published Online: 15 JUL 2009

DOI: 10.1002/9781444316940.ch2

Basic Cardiac Electrophysiology for the Clinician, Second Edition

Basic Cardiac Electrophysiology for the Clinician, Second Edition

How to Cite

Jalife, J., Delmar, M., Anumonwo, J., Berenfeld, O. and Kalifa, J. (2009) Ion Channels, in Basic Cardiac Electrophysiology for the Clinician, Second Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444316940.ch2

Author Information

  1. 1

    The Cyrus and Jane Farrehi Professor of Cardiovascular Research, University of Michigan, Ann Arbor, Michigan, USA

  2. 2

    Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA

  3. 3

    Frank Norman Wilson Professor of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA

  4. 4

    Molecular & Integrative Physiology Co-Director, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA

  5. 5

    Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA

Publication History

  1. Published Online: 15 JUL 2009
  2. Published Print: 29 MAY 2009

ISBN Information

Print ISBN: 9781405183338

Online ISBN: 9781444316940

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Keywords:

  • ion channels;
  • cardiac electrical excitation - Na, K, Ca, and Cl ions;
  • ion permeation mechanisms;
  • ion channel selectivity;
  • Na channel blocking antiarrhythmic agents;
  • transient outward current;
  • pacemaker (“funny”) current;
  • gap junctional current;
  • cardiac ion channel molecular structure

Summary

This chapter contains sections titled:

  • Mechanisms of Ion Permeation

  • Ionic Currents in Cardiac Cells

  • Molecular Structure of Cardiac Ion Channels

  • Summary