Chapter 7. Rotors, Spirals, and Scroll Waves in the Heart

  1. José Jalife MD Professor of Internal Medicine Professor of Molecular & Integrative Physiology1,2,
  2. Mario Delmar MD, PhD Professor of Internal Medicine3,4,
  3. Justus Anumonwo PhD Assistant Professor of Internal Medicine5,
  4. Omer Berenfeld PhD Assistant Professor of Internal Medicine and Biomedical Engineering5 and
  5. Jérôme Kalifa MD, PhD Assistant Professor of Internal Medicine5

Published Online: 15 JUL 2009

DOI: 10.1002/9781444316940.ch7

Basic Cardiac Electrophysiology for the Clinician, Second Edition

Basic Cardiac Electrophysiology for the Clinician, Second Edition

How to Cite

Jalife, J., Delmar, M., Anumonwo, J., Berenfeld, O. and Kalifa, J. (2009) Rotors, Spirals, and Scroll Waves in the Heart, in Basic Cardiac Electrophysiology for the Clinician, Second Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444316940.ch7

Author Information

  1. 1

    The Cyrus and Jane Farrehi Professor of Cardiovascular Research, University of Michigan, Ann Arbor, Michigan, USA

  2. 2

    Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA

  3. 3

    Frank Norman Wilson Professor of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA

  4. 4

    Molecular & Integrative Physiology Co-Director, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA

  5. 5

    Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA

Publication History

  1. Published Online: 15 JUL 2009
  2. Published Print: 29 MAY 2009

ISBN Information

Print ISBN: 9781405183338

Online ISBN: 9781444316940

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Keywords:

  • rotors - reentrant arrhythmias in atria and ventricles;
  • Belousov–Zhabotinski (B–Z) reaction and oscillatory chemical reaction;
  • “Wavebreak” concept;
  • wavelength (WL) of excitation and action potential duration (APD);
  • wavebreaks and “Singularities”;
  • self-sustaining spiral wave activity;
  • figure-of-8 reentry and common pathway;
  • drifting spirals and electrocardiographic patterns;
  • three-dimensional vortex-like reentry in cardiac muscle

Summary

This chapter contains sections titled:

  • Self-Organization in Excitable Media

  • Lessons about Cardiac Reentry from the B-Z Reaction

  • The Concept of “Wavebreak”

  • The Ever-Increasing Curvature of a Spiral Wave Front

  • Wavebreaks and “Singularities”

  • Lines of Block in Anisotropic Reentry

  • Spiral Waves and Wavelets

  • Wavebreak Precedes the Initiation of Reentry

  • Excitability and Core Size

  • The Excitable Gap

  • Figure-of-8 Reentry and the Common Pathway

  • Drifting Spirals

  • Drifting Spirals and Electrocardiographic Patterns

  • Doppler Effect and Torsades de Pointes

  • Anchoring and the Transition from Polymorphic to Monomorphic Activation

  • Effects of Externally Applied Waves on Spiral Wave Dynamics

  • Three-Dimensional Scrolls

  • Dynamics of Scroll Waves

  • Experimental Detection of Three-Dimensional Vortex-like Reentry in Cardiac Muscle

  • Summary