Chapter 104. Osmotic Demyelination Syndromes

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Ovidiu Bajenaru MD, PhD Professor of Neurology Chairman Head

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch104

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Bajenaru, O. (2009) Osmotic Demyelination Syndromes, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch104

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. University Hospital of Emergency, Bucharest, Romania

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008

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Keywords:

  • osmotic demyelination syndrome (ODS) - clinicopathologic entity;
  • ODS, not a common medical condition;
  • ODS, consequence of hyperosmotically-induced demyelination process;
  • chronic hyponatremia - most frequent condition associated with ODS;
  • modern non-invasive imaging techniques;
  • ODS developing after aggressive treatment of hyponatremia;
  • supportive treatment recommended

Summary

This chapter contains sections titled:

  • Introduction

  • Epidemiology

  • Pathophysiology

  • Clinical features

  • Investigations

  • Treatment

  • Further reading