Chapter 112. Acquired Neuropathies

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief3,4,
  2. Daniel D. Truong MD, FAAN Head5,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head6 and
  4. Roongroj Bhidayasiri MD, FRCP Director7,8
  1. Friedhelm Sandbrink MD Assistant Professor in Neurology Director Chief1,2

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch112

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Sandbrink, F. (2009) Acquired Neuropathies, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch112

Editor Information

  1. 3

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 4

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 5

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 6

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 7

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 8

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. 1

    Veterans Affairs Medical Center, Washington, USA

  2. 2

    Georgetown University, Washington, USA

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • acquired neuropathies;
  • Guillain–Barré syndrome (GBS);
  • acute inflammatory demyelinating polyneuropathy (AIDP) - most common subtype;
  • epitopes implicated in Miller–Fisher syndrome - GQ1b and GT1a;
  • GBS distinguished from other conditions - with subacute motor weakness;
  • CSF finding, protein elevation in setting of normal cell count;
  • elevated serum antibodies and positive stool culture for C. jejuni and serological testing for Epstein–Barr virus;
  • multifocal motor neuropathy (MMN), a rare disease mimicking motor neuron disorder


This chapter contains sections titled:

  • Immune-mediated neuropathies

  • Chronic inflammatory demyelinating polyneuropathy (CIDP)

  • Metabolic neuropathies

  • Infectious neuropathies

  • Neuropathy from nutritional causes and alcoholism

  • Further reading