Chapter 130. Low Grade Astrocytoma

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Martin J. van den Bent MD Neurologist Head

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch130

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

van den Bent, M. J. (2009) Low Grade Astrocytoma, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch130

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. Erasmus University Medical Center, Rotterdam, The Netherlands

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • low grade astrocytoma;
  • astrocytomas, constituting diffuse glioma;
  • large phase III studies - on low grade glioma identified astrocytic histology;
  • astrocytoma treatment and management;
  • neuroradiological diagnosis of presumable low grade glioma;
  • patients with focal deficits, raised intracranial pressure - requiring treatment without undue delay;
  • young patients with unenhancing intracerebral lesion - suspected as lowgrade glioma without mass effect


This chapter contains sections titled:

  • Introduction

  • Epidemiology and clinical features

  • Pathology and molecular biology

  • Investigations

  • Prognosis

  • Treatment and management of astrocytoma

  • Further reading