Chapter 149. REM Behavior Disorder (RBD)

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Li Ling Lim MBBS, MRCP (UK), MPH (USA), Dip. ABPN, ABSM, ABEM, ABCN (USA) Medical Director Consultant Neurologist

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch149

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Ling Lim, L. (2009) REM Behavior Disorder (RBD), in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch149

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. Gleneagles Medical Centre, Singapore

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • REM behavior disorder (RBD);
  • Rapid eye movement (REM) sleep behavior disorder (RBD) - most common REM sleep parasomnia;
  • Positron emission tomography (PET) and single photon emission computed tomography (SPECT);
  • RBD, manifesting as complex dream-enacting behaviors - often vivid, unpleasant, or violent, as being attacked or chased;
  • dementia with Lewy bodies (DLB);
  • RBD, slowly progressive - rarely associated with spontaneous remissions;
  • PSG with time-synchronized video-EEG recording - to document typical PSG features of RBD;
  • RBD, most common REM parasomnia - neurodegeneration, affecting primarily older men;
  • PSG with time-synchronized video-EEG recording - documenting PSG features of RBD


This chapter contains sections titled:

  • Introduction

  • Epidemiology and risk factors

  • Pathophysiology

  • Clinical features and differential diagnoses

  • Investigations

  • Management

  • Clinical course

  • Summary

  • Further reading