Chapter 20. Cerebrovascular Disease Associated with Antiphospholipid Antibodies

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Megan Alcauskas MD Resident and
  2. Steven R. Levine MD Professor of Neurology

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch20

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Alcauskas, M. and Levine, S. R. (2009) Cerebrovascular Disease Associated with Antiphospholipid Antibodies, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch20

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. Department of Neurology and Stroke Center, The Mount Sinai School of Medicine and Medical Center, New York, NY, USA

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • antiphospholipid antibodies (aPL) associated cerebrovascular disease;
  • aPL - autoantibodies against phospholipids and phospholipid-binding proteins;
  • aPL and increased thrombosis risk;
  • aPL prevalence in young, healthy people;
  • APS - antiphospholipid antibody syndrome;
  • APS clinical manifestation - deep venous thrombosis of leg;
  • APS management, in non-pregnant patients - low-dose aspirin therapy


This chapter contains sections titled:

  • Introduction

  • Epidemiology

  • Pathophysiology

  • Clinical features

  • Diagnosis

  • Management

  • Further reading