Chapter 25. Behçet's Syndrome and the Nervous System

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Aksel Siva MD Professor of Neurology Head and
  2. Sabahattin Saip MD Professor of Neurology

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch25

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Siva, A. and Saip, S. (2009) Behçet's Syndrome and the Nervous System, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch25

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. Clinical Neuroimmunology Unit, Department of Neurology, Cerrahpaşa School of Medicine, University of Istanbul, Istanbul, Turkey

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008

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Keywords:

  • Behçet's syndrome, nervous system;
  • Behçet's disease - idiopathic chronic relapsing multisystem vascular-inflammatory disease;
  • human leukocyte antigen HLA-B51 - geographic distribution of Behçet's syndrome;
  • major pathophysiologic changes – excessive functions of neutrophils, endothelial injury with vasculitis, autoimmune responses;
  • cyclosporine - causing neurotoxicity/accelerating development of CNS symptoms;
  • Mycophenolate mofetil, tacrolimus - immunosuppressant/ immunomodulating agents treating ocular inflammation

Summary

This chapter contains sections titled:

  • Introduction

  • Nervous system involvement in Behçet's disease – “neuro-Behçet's syndrome”

  • Diagnostic studies in NBS

  • Differential diagnosis

  • Prognosis

  • Treatment

  • Further reading