Chapter 26. Sarcoidosis

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Barney J. Stern MD Professor of Neurology

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch26

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Stern, B. J. (2009) Sarcoidosis, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch26

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. Department of Neurology, University of Maryland, Baltimore, MD, USA

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008

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Keywords:

  • sarcoidosis - neurosarcoidosis as diagnostic consideration;
  • sarcoidosis prevalence - 40 per 100 000 population;
  • pathophysiology - epithelioid macrophages, lymphocytes, monocytes, and fibroblasts;
  • neurologic manifestations - cranial neuropathies, meningeal disease;
  • CNS sarcoidosis - elevated angiotensin-converting enzyme (ACE) activity;
  • neurosarcoidosis treatment. - corticosteroid therapy as first-line therapy;
  • immunosuppressive medications - mycophenolate mofetil, azathioprine, methotrexate

Summary

This chapter contains sections titled:

  • Introduction

  • Epidemiology

  • Pathophysiology

  • Clinical features

  • Investigations

  • Treatment/management

  • Further reading