Chapter 3. Atherothrombotic Disease

  1. Robert P. Lisak MD, FAAN, FRCP Parker Webber Chair Professor Chair Neurologist-in-Chief Chief2,3,
  2. Daniel D. Truong MD, FAAN Head4,
  3. William M. Carroll MBBS, MD, FRACP, FRCP(E) Head5 and
  4. Roongroj Bhidayasiri MD, FRCP Director6,7
  1. Nijasri C. Suwanwela MD Associate Professor of Neurology Director

Published Online: 18 MAY 2010

DOI: 10.1002/9781444317008.ch3

International Neurology: A Clinical Approach

International Neurology: A Clinical Approach

How to Cite

Suwanwela, N. C. (2009) Atherothrombotic Disease, in International Neurology: A Clinical Approach (eds R. P. Lisak, D. D. Truong, W. M. Carroll and R. Bhidayasiri), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444317008.ch3

Editor Information

  1. 2

    Wayne State University School of Medicine, Detroit, MI, USA

  2. 3

    Detroit Medical Center, Harper University Hospital, Detroit, MI, USA

  3. 4

    The Parkinson and Movement Disorder Institute, Memorial Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA

  4. 5

    Sir Charles Gairdner Hospital, Nedlands, Perth, Australia

  5. 6

    Chulalongkorn Comprehensive Movement Disorders Center, Chulalongkorn University Hospital, Bangkok, Thailand

  6. 7

    University of California at Los Angeles, School of Medicine, Los Angeles, CA, USA

Author Information

  1. Chulalongkorn Stroke Center, Neurological Unit, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Publication History

  1. Published Online: 18 MAY 2010
  2. Published Print: 11 SEP 2009

ISBN Information

Print ISBN: 9781405157384

Online ISBN: 9781444317008



  • atherothrombotic disease - atheromatous process producing embolic stroke;
  • extracranial arteries atherosclerosis, neck- stroke risk and atherosclerotic plaque characteristics;
  • intracranial arteries atherosclerosis sites - middle cerebral artery;
  • ascending aorta atherosclerosis and embolic stroke;
  • epidemiology - ischemic stroke major cause - atherosclerosis;
  • stroke in atherosclerosis patients - pathophysiology - categories and clinical features;
  • investigations - atherosclerosis diagnosis - artery wall imaging;
  • management - thrombolysis with tissue plasminogen activator (tPA)


This chapter contains sections titled:

  • Introduction

  • Epidemiology

  • Pathophysiology and clinical features

  • Investigations

  • Management

  • Further reading